The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA. - Wikidata - awgldk - TriplyDB

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

http://www.wikidata.org/entity/Q33696467

about

FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51 Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2 Using a Fragment-Based Approach To Target Protein-Protein Interactions High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.Engineering archeal surrogate systems for the development of protein-protein interaction inhibitors against human RAD51 Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins Molding BRCA2 function through its interacting partners Unraveling the mechanism of BRCA2 in homologous recombination Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity Homologs of breast cancer genes in plants Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination.Many ways to loop DNA.Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques.Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction.BRCA2 coordinates the activities of cell-cycle kinases to promote genome stability SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression.The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination.Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.Characterization of Brca2-deficient plants excludes the role of NHEJ and SSA in the meiotic chromosomal defect phenotype.Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.Human nuclease/helicase DNA2 alleviates replication stress by promoting DNA end resection.BRCA2 is a mediator of RAD51- and DMC1-facilitated homologous recombination in Arabidopsis thaliana.RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair.Visualization and quantification of nascent RAD51 filament formation at single-monomer resolution.Cancer suppression by the chromosome custodians, BRCA1 and BRCA2.Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability HOP2-MND1 modulates RAD51 binding to nucleotides and DNA.BLM SUMOylation regulates ssDNA accumulation at stalled replication forks.Cell biology of mitotic recombination.BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.DNA repair mechanisms in cancer development and therapy Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.A protective role for BRCA2 at stalled replication forks.

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P2860

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

http://www.wikidata.org/entity/Q33696467

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The breast cancer tumor suppre ...... RAD51 to single-stranded DNA.

@ast

The breast cancer tumor suppre ...... RAD51 to single-stranded DNA.

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type

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The breast cancer tumor suppre ...... RAD51 to single-stranded DNA.

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The breast cancer tumor suppre ...... RAD51 to single-stranded DNA.

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The breast cancer tumor suppre ...... RAD51 to single-stranded DNA.

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The breast cancer tumor suppre ...... RAD51 to single-stranded DNA.

@en

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P1433

Nature Structural & Molecular Biology

P1476

The breast cancer tumor suppre ...... RAD51 to single-stranded DNA.

@en

P2093

Jack D Griffith

http://www.w3.org/2001/XMLSchema#string

Sarah A Compton

http://www.w3.org/2001/XMLSchema#string

Sergey Lekomtsev

http://www.w3.org/2001/XMLSchema#string

P2860

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2

Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

Rad52 protein associates with replication protein A (RPA)-single-stranded DNA to accelerate Rad51-mediated displacement of RPA and presynaptic complex formation.

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1263-1265

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scholarly article

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10.1038/NSMB.1905

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10

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17

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Mark Petronczki

Michael J McIlwraith

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2010-08-22T00:00:00Z

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20729858

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4041013

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