Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. - Wikidata - awgldk - TriplyDB

Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation.

Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation.

http://www.wikidata.org/entity/Q33747915

about

Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets Oxidized PLs and vascular inflammation Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid Functional and pathological roles of the 12- and 15-lipoxygenases Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase.Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.Chronic alcohol exposure increases circulating bioactive oxidized phospholipids.Mechanisms for anti-inflammatory effects of 1-[15(S)-hydroxyeicosapentaenoyl] lysophosphatidylcholine, administered intraperitoneally, in zymosan A-induced peritonitis A novel role for 12/15-lipoxygenase in regulating autophagy Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids.Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation.Formation and signaling actions of electrophilic lipids A simplified procedure for semi-targeted lipidomic analysis of oxidized phosphatidylcholines induced by UVA irradiation.Oxidatively truncated phospholipids are required agents of tumor necrosis factor α (TNFα)-induced apoptosis.12(S)-HETrE, a 12-Lipoxygenase Oxylipin of Dihomo-γ-Linolenic Acid, Inhibits Thrombosis via Gαs Signaling in Platelets New families of bioactive oxidized phospholipids generated by immune cells: identification and signaling actions.Protease-activated receptors (PARs)--biology and role in cancer invasion and metastasis.LipidFinder: A computational workflow for discovery of lipids identifies eicosanoid-phosphoinositides in platelets.Investigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation.Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A2 as a Regulator of Mitochondrial Bioenergetics during Activation.Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation.Oxidized fatty acid analysis by charge-switch derivatization, selected reaction monitoring, and accurate mass quantitation.DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression.Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase Esterified eicosanoids: generation, characterization and function.Bioactive oxidatively truncated phospholipids in inflammation and apoptosis: formation, targets, and inactivation Role of phospholipid oxidation products in atherosclerosis.The role of mid-chain hydroxyeicosatetraenoic acids in the pathogenesis of hypertension and cardiac hypertrophy.Who is the real 12-HETrE?The expansive role of oxylipins on platelet biology.Combined Quantification of the Global Proteome, Phosphoproteome, and Proteolytic Cleavage to Characterize Altered Platelet Functions in the Human Scott Syndrome.Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS

P2860

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P2860

Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation.

http://www.wikidata.org/entity/Q33747915

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Phospholipid-esterified eicosa ...... dependent thrombin generation.

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Phospholipid-esterified eicosa ...... dependent thrombin generation.

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type

label

Phospholipid-esterified eicosa ...... dependent thrombin generation.

@ast

Phospholipid-esterified eicosa ...... dependent thrombin generation.

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prefLabel

Phospholipid-esterified eicosa ...... dependent thrombin generation.

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Phospholipid-esterified eicosa ...... dependent thrombin generation.

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Journal of Biological Chemistry

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Phospholipid-esterified eicosa ...... dependent thrombin generation.

@en

P2093

Benjamin H Maskrey

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Hartmut Kühn

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Hassan A Hamali

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Lloyd T Morgan

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Peter W Collins

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Stanley L Hazen

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P2860

Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis

G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2

The diversity of the lipoxygenase family. Many sequence data but little information on biological significance.

Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2.

Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease.

Bioactive products of phospholipid oxidation: isolation, identification, measurement and activities.

A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria.

Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.

Activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase.

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress.

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6891-6903

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Christopher P. Thomas

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Valerie O'Donnell

Alison H Goodall

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2010-01-08T00:00:00Z

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40899136

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20061396

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