Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade - Wikidata - awgldk - TriplyDB

Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade

Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade

http://www.wikidata.org/entity/Q33777725

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The PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.Synapse-specific contributions in the cortical pathology of schizophrenia DISC1: a key lead in studying cortical development and associated brain disorders DISC1-binding proteins in neural development, signalling and schizophrenia DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1.Potential primary roles of glial cells in the mechanisms of psychiatric disorders.Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion.Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects.In vivo imaging of adult human hippocampal neurogenesis: progress, pitfalls and promise Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.Occludin deficiency with BACE1 elevation in cerebral amyloid angiopathy.The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain DISC1 in schizophrenia: genetic mouse models and human genomic imaging.Linking neurodevelopmental and synaptic theories of mental illness through DISC1 Microglial dysregulation in psychiatric disease Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia.DISC1 (disrupted-in-schizophrenia-1) regulates differentiation of oligodendrocytes DISC1 is associated with cortical thickness and neural efficiency Brain in flames - animal models of psychosis: utility and limitations Aggregated proteins in schizophrenia and other chronic mental diseases: DISC1opathies Sonic hedgehog functions upstream of disrupted-in-schizophrenia 1 (disc1): implications for mental illness.Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex.Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.DISC1 genetics, biology and psychiatric illness Utility and validity of DISC1 mouse models in biological psychiatry.Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate control Disrupted-in-Schizophrenia-1 Attenuates Amyloid-β Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of β-Site APP-Cleaving Enzyme 1 Levels.Integrative mechanisms of oriented neuronal migration in the developing brain.The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review.Electrical Stimulation Using Conductive Polymer Polypyrrole Counters Reduced Neurite Outgrowth of Primary Prefrontal Cortical Neurons from NRG1-KO and DISC1-LI Mice.The Membrane-Bound Aspartyl Protease BACE1: Molecular and Functional Properties in Alzheimer's Disease and Beyond Schizophrenia genetics: putting all the pieces together.Microglia as modulators of cognition and neuropsychiatric disorders.Progress in imaging the effects of psychosis susceptibility gene variants.BACE1 as a therapeutic target in Alzheimer's disease: rationale and current status.Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system.Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases

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P2860

Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade

http://www.wikidata.org/entity/Q33777725

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2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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Disrupted-in-Schizophrenia-1 e ...... ng enzyme-1-neuregulin cascade

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Akiko Hayashi-Takagi

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Akira Sawa

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Amelia Stanco

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Atsushi Kamiya

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Carsten Korth

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E S Anton

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Ingrid Prikulis

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Koko Ishizuka

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Philip Wong

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Sarada Rao

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P2860

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia

DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease

Neuregulin 1 and susceptibility to schizophrenia.

Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia

Control of peripheral nerve myelination by the beta-secretase BACE1

Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease

Disruption of GW bodies impairs mammalian RNA interference

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5622-5627

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