Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells
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Specification and function of hemogenic endothelium during embryogenesisThe RUNX1 +24 enhancer and P1 promoter identify a unique subpopulation of hematopoietic progenitor cells derived from human pluripotent stem cellsActivation of HIV-1 from latent infection via synergy of RUNX1 inhibitor Ro5-3335 and SAHAQuiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1.A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation.Abrogation of RUNX1 gene expression in de novo myelodysplastic syndrome with t(4;21)(q21;q22).Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects.Transcription Factor RUNX1 Regulates Platelet PCTP (Phosphatidylcholine Transfer Protein): Implications for Cardiovascular Events.Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in miceDnmt3a is essential for hematopoietic stem cell differentiation.TGF-β superfamily gene expression and induction of the Runx1 transcription factor in adult neurogenic regions after brain injury.High fat diet rapidly suppresses B lymphopoiesis by disrupting the supportive capacity of the bone marrow niche.Investigating the role of hematopoietic stem and progenitor cells in regulating the osteogenic differentiation of mesenchymal stem cells in vitro.Donor Dependent Variations in Hematopoietic Differentiation among Embryonic and Induced Pluripotent Stem Cell Lines.RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cellsEnforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo.Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling.Hematopoietic stem cell emergence in the conceptus and the role of Runx1.New insights into the role of Runx1 in epithelial stem cell biology and pathology.Expression of different functional isoforms in haematopoiesis.HOXB4 Increases Runx1 Expression to Promote the de novo Formation of Multipotent Hematopoietic Cells.Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells.DNA methylation in normal and malignant hematopoiesis.Dnmt3a regulates T-cell development and suppresses T-ALL transformation.Runx1 Structure and Function in Blood Cell Development.Role of RUNX1 in hematological malignancies.The Role of Runx1 in Embryonic Blood Cell Formation.RUNX1 cooperates with FLT3-ITD to induce leukemia.Tyrosyl phosphorylation toggles a Runx1 switch.Identification of a novel fusion gene involving RUNX1 and the antisense strand of SV2B in a BCR-ABL1-positive acute leukemia.Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells.Regulation of RUNX1 Expression and ActivitySingle Cell Resolution of Human Hematoendothelial Cells Defines Transcriptional Signatures of Hemogenic Endothelium.Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation.RUNX1c Regulates Hematopoietic Differentiation of Human Pluripotent Stem Cells Possibly in Cooperation with Proinflammatory Signaling.Precocious Phenotypic Transcription-Factor Expression During Early Development.Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium.Abnormal folate metabolism causes age-, sex- and parent-of-origin-specific haematological defects in mice
P2860
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P2860
Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Runx1 isoforms show differenti ...... adult hematopoietic stem cells
@ast
Runx1 isoforms show differenti ...... adult hematopoietic stem cells
@en
type
label
Runx1 isoforms show differenti ...... adult hematopoietic stem cells
@ast
Runx1 isoforms show differenti ...... adult hematopoietic stem cells
@en
prefLabel
Runx1 isoforms show differenti ...... adult hematopoietic stem cells
@ast
Runx1 isoforms show differenti ...... adult hematopoietic stem cells
@en
P2860
P1476
Runx1 isoforms show differenti ...... adult hematopoietic stem cells
@en
P2093
Grant A Challen
P2860
P304
P356
10.1016/J.EXPHEM.2010.02.011
P577
2010-03-03T00:00:00Z