Rapamycin extends maximal lifespan in cancer-prone mice. - Wikidata - awgldk - TriplyDB

Rapamycin extends maximal lifespan in cancer-prone mice.

Rapamycin extends maximal lifespan in cancer-prone mice.

http://www.wikidata.org/entity/Q33816255

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Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Mitochondrial biology and Parkinson's disease Rapalogs in cancer prevention: anti-aging or anticancer?Pathobiology of aging mice and GEM: background strains and experimental design Disruptive chemicals, senescence and immortality Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine Autophagy and cardiovascular aging: lesson learned from rapamycin.Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake Quality control systems in cardiac aging Intermittent Administration of Rapamycin Extends the Life Span of Female C57BL/6J Mice Rapalogs and mTOR inhibitors as anti-aging therapeutics Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin Mitochondrial dysfunction in cardiac aging Staying young at heart: autophagy and adaptation to cardiac aging Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells.Rapamycin extends murine lifespan but has limited effects on aging.Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice Latest progress in tyrosine kinase inhibitors Growth factors, aging and age-related diseases.From rapalogs to anti-aging formula.The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer Why human lifespan is rapidly increasing: solving "longevity riddle" with "revealed-slow-aging" hypothesis.Hormesis, cell death and aging.Rapamycin slows aging in mice Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications Berberine suppresses gero-conversion from cell cycle arrest to senescence.TOR-centric view on insulin resistance and diabetic complications: perspective for endocrinologists and gerontologists.Longevity, aging and rapamycin.Environmental cadmium and breast cancer risk.Rapamycin-induced metabolic defects are reversible in both lean and obese mice Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system.Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling Lifespan modulation in mice and the confounding effects of genetic background.Normalizing a hyperactive mTOR initiates muscle growth during obesity Linking nutrition, maturation and aging: from thrifty genes to the spendthrift phenotype Gerosuppression in confluent cells.Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet

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Rapamycin extends maximal lifespan in cancer-prone mice.

http://www.wikidata.org/entity/Q33816255

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Rapamycin extends maximal lifespan in cancer-prone mice.

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Rapamycin extends maximal lifespan in cancer-prone mice.

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type

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Rapamycin extends maximal lifespan in cancer-prone mice.

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Rapamycin extends maximal lifespan in cancer-prone mice.

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prefLabel

Rapamycin extends maximal lifespan in cancer-prone mice.

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Rapamycin extends maximal lifespan in cancer-prone mice.

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AJPATH.2010.091050

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The American Journal of Pathology

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Rapamycin extends maximal lifespan in cancer-prone mice.

@en

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Anna V Semenchenko

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Irina G Popovich

http://www.w3.org/2001/XMLSchema#string

Margarita L Tyndyk

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Maria N Yurova

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Marina P Antoch

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Mark A Zabezhinski

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Tatiana S Piskunova

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Vladimir N Anisimov

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P2860

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Caloric restriction delays disease onset and mortality in rhesus monkeys

TOR signaling in growth and metabolism

Genetic pathways that regulate ageing in model organisms

The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

Genetics: influence of TOR kinase on lifespan in C. elegans

Validation of anti-aging drugs by treating age-related diseases.

The age of cancer.

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176

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Mikhail Blagosklonny

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42975769

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20363920

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2861075

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