The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
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Main roads to melanomaPhosphorylation of the PTEN tail regulates protein stability and functionPTEN function: how normal cells control it and tumour cells lose itPKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer.A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Review on molecular and chemopreventive potential of nimbolide in cancerThe complement of protein phosphatase catalytic subunits encoded in the genome of ArabidopsisPTEN knockdown alters dendritic spine/protrusion morphology, not densityCell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cellsIdentification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis.Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line.Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma.Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinomaMicroRNA-382 induced by HIF-1α is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog.Modulation in activation and expression of phosphatase and tensin homolog on chromosome ten, Akt1, and 3-phosphoinositide-dependent kinase 1: further evidence demonstrating altered phosphoinositide 3-kinase signaling in postmortem brain of suicide sRapid estrogen signaling negatively regulates PTEN activity through phosphorylation in endometrial cancer cells.Activation of dormant ovarian follicles to generate mature eggsEpigenetic inactivation of inositol polyphosphate 4-phosphatase B (INPP4B), a regulator of PI3K/AKT signaling pathway in EBV-associated nasopharyngeal carcinomaDecreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signalingPTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migrationFunctional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.The basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators.Tumor suppressor PTEN acts through dynamic interaction with the plasma membraneEnteropathogenic Escherichia coli mediates antiphagocytosis through the inhibition of PI 3-kinase-dependent pathways.Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair.The linker pivot in Ci-VSP: the key to unlock catalysisAcid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling.Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT modelTargeting the phosphatidylinositol 3-kinase signaling pathway in breast cancer.S-nitrosylation of mixed lineage kinase 3 contributes to its activation after cerebral ischemia.Current progress of siRNA/shRNA therapeutics in clinical trials.EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expressionActivation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells.Nontranscriptional activation of PI3K/Akt signaling mediates hypotensive effect following activation of estrogen receptor β in the rostral ventrolateral medulla of rats.PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kappaB signaling pathway in human glioma cellsThe association between phosphatase and tensin homolog hypermethylation and patients with breast cancer, a meta-analysis and literature review.Bypass of hexavalent chromium-induced growth arrest by a protein tyrosine phosphatase inhibitor: enhanced survival and mutagenesis.
P2860
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P2860
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
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2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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name
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
@ast
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
@en
type
label
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
@ast
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
@en
prefLabel
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
@ast
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
@en
P1476
The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
@en
P2093
W R Sellers
P304
P356
10.1016/S0304-419X(99)00032-3
P407
P577
2000-02-01T00:00:00Z