Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity.
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Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosaFunctional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteasesThe roles of intramembrane proteases in protozoan parasitesHydrogen bond dynamics in membrane protein functionMaking the cut: central roles of intramembrane proteolysis in pathogenic microorganismsAnalysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genomeStructural basis for intramembrane proteolysis by rhomboid serine proteasesOpen-cap conformation of intramembrane protease GlpGThe Role of L1 Loop in the Mechanism of Rhomboid Intramembrane Protease GlpGThe structural basis for catalysis and substrate specificity of a rhomboid proteaseStructure of Rhomboid Protease in a Lipid EnvironmentActivity-based probes for rhomboid proteases discovered in a mass spectrometry-based assayStructure of Rhomboid Protease in Complex with β-Lactam Inhibitors Defines the S2′ CavityProteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate AffinityTwo Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malariaA C-terminal region of signal peptide peptidase defines a functional domain for intramembrane aspartic protease catalysisA Trichomonas vaginalis Rhomboid Protease and Its Substrate Modulate Parasite Attachment and Cytolysis of Host CellsMembrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Structures of membrane proteins.Structure and mechanism of rhomboid proteaseOpa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.An internal water-retention site in the rhomboid intramembrane protease GlpG ensures catalytic efficiency.RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer.Monocyclic β-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteasesA spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma.Downregulation of an Entamoeba histolytica rhomboid protease reveals roles in regulating parasite adhesion and phagocytosisDependency of γ-secretase complex activity on the structural integrity of the bilayer.Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structuresStage-specific expression of protease genes in the apicomplexan parasite, Eimeria tenellaFunctional characterization of Escherichia coli GlpG and additional rhomboid proteins using an aarA mutant of Providencia stuartii.Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate.An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion.A new class of rhomboid protease inhibitors discovered by activity-based fluorescence polarizationHax1 lacks BH modules and is peripherally associated to heavy membranes: implications for Omi/HtrA2 and PARL activity in the regulation of mitochondrial stress and apoptosis.A subset of membrane-altering agents and γ-secretase modulators provoke nonsubstrate cleavage by rhomboid proteasesTaking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysisDerlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum.Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate.Cooperative folding of a polytopic α-helical membrane protein involves a compact N-terminal nucleus and nonnative loops.From rhomboid function to structure and back again
P2860
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P2860
Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Reconstitution of intramembran ...... for catalysis and specificity.
@ast
Reconstitution of intramembran ...... for catalysis and specificity.
@en
type
label
Reconstitution of intramembran ...... for catalysis and specificity.
@ast
Reconstitution of intramembran ...... for catalysis and specificity.
@en
prefLabel
Reconstitution of intramembran ...... for catalysis and specificity.
@ast
Reconstitution of intramembran ...... for catalysis and specificity.
@en
P2860
P356
P1476
Reconstitution of intramembran ...... for catalysis and specificity.
@en
P2093
Michael S Wolfe
Sinisa Urban
P2860
P304
P356
10.1073/PNAS.0408306102
P407
P577
2005-01-31T00:00:00Z