Origin of chromosomal translocations in lymphoid cancer.
about
Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphomaMutational processes molding the genomes of 21 breast cancersUnbalanced replication as a major source of genetic instability in cancer cellsAtaxia-telangiectasia: future prospectsThe consequences of chromosomal aneuploidy on the transcriptome of cancer cellsRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationImpact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaksSequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 BindingThe DNA Damage Response: Making It Safe to Play with KnivesEffect of nuclear architecture on the efficiency of double-strand break repair.The biology behind PI3K inhibition in chronic lymphocytic leukaemiaRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeMammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrityThe response to and repair of RAG-mediated DNA double-strand breaksHomology and enzymatic requirements of microhomology-dependent alternative end joiningAID targeting: old mysteries and new challengesRole of non-homologous end joining in V(D)J recombinationPTIP promotes chromatin changes critical for immunoglobulin class switch recombinationAntibody-siRNA conjugates: drugging the undruggable for anti-leukemic therapy.Generation and repair of AID-initiated DNA lesions in B lymphocytes.Repair of DNA double-strand breaks by templated nucleotide sequence insertions derived from distant regions of the genome.Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytesNew Insights in the Cytogenetic Practice: Karyotypic Chaos, Non-Clonal Chromosomal Alterations and Chromosomal Instability in Human Cancer and Therapy ResponseAID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants.Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centersMobile elements and viral integrations prompt considerations for bacterial DNA integration as a novel carcinogenRegulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation.Identification of chromosomal translocation hotspots via scan statisticsMechanisms that can promote peripheral B-cell lymphoma in ATM-deficient mice.The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.Roles for histone H3K4 methyltransferase activities during immunoglobulin class-switch recombinationActivation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice.AID-initiated DNA lesions are differentially processed in distinct B cell populations.The AID-induced DNA damage response in chromatin.B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.Epigenetic targeting of activation-induced cytidine deaminase.
P2860
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P2860
Origin of chromosomal translocations in lymphoid cancer.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Origin of chromosomal translocations in lymphoid cancer.
@ast
Origin of chromosomal translocations in lymphoid cancer.
@en
type
label
Origin of chromosomal translocations in lymphoid cancer.
@ast
Origin of chromosomal translocations in lymphoid cancer.
@en
prefLabel
Origin of chromosomal translocations in lymphoid cancer.
@ast
Origin of chromosomal translocations in lymphoid cancer.
@en
P2860
P1433
P1476
Origin of chromosomal translocations in lymphoid cancer.
@en
P2093
André Nussenzweig
P2860
P356
10.1016/J.CELL.2010.03.016
P407
P577
2010-04-01T00:00:00Z