Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumor suppressor protein.
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The modulation of apoptosis by oncogenic virusesInteraction between the HPV-16 E2 transcriptional activator and p53.The molecular genetics of cervical carcinoma.Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell linesProductive replication of adeno-associated virus can occur in human papillomavirus type 16 (HPV-16) episome-containing keratinocytes and is augmented by the HPV-16 E2 protein.Proteasome-mediated degradation of the papillomavirus E2-TA protein is regulated by phosphorylation and can modulate viral genome copy number.HPV-16 E2 gene disruption and sequence variation in CIN 3 lesions and invasive squamous cell carcinomas of the cervix: relation to numerical chromosome abnormalities.Squamous metaplasia induced by transfection of human papillomavirus DNA into cultured adenocarcinoma cells.A splicing enhancer in the E4 coding region of human papillomavirus type 16 is required for early mRNA splicing and polyadenylation as well as inhibition of premature late gene expression.Transcriptional activity among high and low risk human papillomavirus E2 proteins correlates with E2 DNA binding.Identification of a G(2) arrest domain in the E1 wedge E4 protein of human papillomavirus type 16.Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cellsE2 proteins from high- and low-risk human papillomavirus types differ in their ability to bind p53 and induce apoptotic cell death.Adeno-associated virus type 2 increases proteosome-dependent degradation of p21WAF1 in a human papillomavirus type 31b-positive cervical carcinoma lineCharacterization of the methylation patterns in human papillomavirus type 16 viral DNA in head and neck cancers.Re-expression of HPV16 E2 in SiHa (human cervical cancer) cells potentiates NF-κB activation induced by TNF-α concurrently increasing senescence and survivalReplication and partitioning of papillomavirus genomes.Molecular events in uterine cervical cancer.Identification and analysis of papillomavirus E2 protein binding sites in the human genome.Human papillomavirus E7 repression in cervical carcinoma cells initiates a transcriptional cascade driven by the retinoblastoma family, resulting in senescence.Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways.Effects of Methylation Status of CpG Sites within the HPV16 Long Control Region on HPV16-Positive Head and Neck Cancer CellsChromosome 17 aneusomy detected by fluorescence in situ hybridization in vulvar squamous cell carcinomas and synchronous vulvar skin.The Replicative Consequences of Papillomavirus E2 Protein Binding to the Origin Replication Factor ORC2P53 represses human papillomavirus type 16 DNA replication via the viral E2 proteinEvolutionary and biophysical relationships among the papillomavirus E2 proteins.Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells.The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer.Human papillomaviruses: a growing fieldHuman papillomavirus early proteins and apoptosis.Human papillomavirus oncoproteins and apoptosis (Review).Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression.Differential requirements for conserved E2 binding sites in the life cycle of oncogenic human papillomavirus type 31p53 and hTERT determine sensitivity to viral apoptosisThe human papillomavirus (HPV) 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway.
P2860
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P2860
Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumor suppressor protein.
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Abrogation of a mitotic checkp ...... p53 tumor suppressor protein.
@ast
Abrogation of a mitotic checkp ...... p53 tumor suppressor protein.
@en
type
label
Abrogation of a mitotic checkp ...... p53 tumor suppressor protein.
@ast
Abrogation of a mitotic checkp ...... p53 tumor suppressor protein.
@en
prefLabel
Abrogation of a mitotic checkp ...... p53 tumor suppressor protein.
@ast
Abrogation of a mitotic checkp ...... p53 tumor suppressor protein.
@en
P2093
P2860
P356
P1433
P1476
Abrogation of a mitotic checkp ...... e p53 tumor suppressor protein
@en
P2093
L A Laimins
M G Frattini
P2860
P304
P356
10.1093/EMBOJ/16.2.318
P407
P577
1997-01-01T00:00:00Z