Functional interaction between the Werner Syndrome protein and DNA polymerase delta
about
Werner SyndromeWerner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activityColocalization, physical, and functional interaction between Werner and Bloom syndrome proteinsPhysical and functional interaction of the Werner syndrome protein with poly-ADP ribosyl transferaseIdentification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1Werner syndrome protein interacts functionally with translesion DNA polymerasesIdentification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta.The RecQ DNA helicases in DNA repairAnalysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein ARoles of Werner syndrome protein in protection of genome integrityModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesThe Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase deltaWerner protein recruits DNA polymerase delta to the nucleolusHuman premature aging, DNA repair and RecQ helicasesexo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair.Mediation of proliferating cell nuclear antigen (PCNA)-dependent DNA replication through a conserved p21(Cip1)-like PCNA-binding motif present in the third subunit of human DNA polymerase deltaRegulation of the Werner helicase through a direct interaction with a subunit of protein kinase AReconstitution of human DNA polymerase delta using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzymeThe processing of Holliday junctions by BLM and WRN helicases is regulated by p53A novel protein interacts with the Werner's syndrome gene product physically and functionallyThe Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δPOLD1 Germline Mutations in Patients Initially Diagnosed with Werner SyndromeAge-dependent down-regulation of DNA polymerase δ1 in human lymphocytesEvidence for a replication function of FFA-1, the Xenopus orthologue of Werner syndrome protein.RecQ helicases: guardian angels of the DNA replication fork.Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D.Differential regulation of human RecQ family helicases in cell transformation and cell cycle.Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle.Acetylation of Werner syndrome protein (WRN): relationships with DNA damage, DNA replication and DNA metabolic activities.Interactions of DNA helicases with damaged DNA: possible biological consequences.Mouse WRN Helicase Domain Is Not Required for Spontaneous Homologous Recombination-Mediated DNA DeletionWRN helicase accelerates the transcription of ribosomal RNA as a component of an RNA polymerase I-associated complex.Characterization of the DNA-unwinding activity of human RECQ1, a helicase specifically stimulated by human replication protein A.The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA.Monogenic syndromes of abnormal glucose homeostasis: clinical review and relevance to the understanding of the pathology of insulin resistance and beta cell failure.Further characterization of human DNA polymerase delta interacting protein 38.Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication.Molecular bases of progeroid syndromes.
P2860
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P2860
Functional interaction between the Werner Syndrome protein and DNA polymerase delta
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Functional interaction between the Werner Syndrome protein and DNA polymerase delta
@ast
Functional interaction between the Werner Syndrome protein and DNA polymerase delta
@en
type
label
Functional interaction between the Werner Syndrome protein and DNA polymerase delta
@ast
Functional interaction between the Werner Syndrome protein and DNA polymerase delta
@en
prefLabel
Functional interaction between the Werner Syndrome protein and DNA polymerase delta
@ast
Functional interaction between the Werner Syndrome protein and DNA polymerase delta
@en
P2093
P2860
P356
P1476
Functional interaction between the Werner Syndrome protein and DNA polymerase delta
@en
P2093
A S Kamath-Loeb
E Johansson
P M Burgers
P2860
P304
P356
10.1073/PNAS.97.9.4603
P407
P577
2000-04-01T00:00:00Z