Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases - Wikidata - awgldk - TriplyDB

Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases

Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases

http://www.wikidata.org/entity/Q33926052

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Fluid shear stress-induced osteoarthritis: roles of cyclooxygenase-2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinases Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis.Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation.Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2.Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1.Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways.Cardiac-generated prostanoids mediate cardiac myocyte apoptosis after myocardial ischaemia Comparative proteome analysis of abdominal adipose tissues between fat and lean broilers.Lubricin restoration in a mouse model of congenital deficiency.The antagonistic actions of endogenous interleukin-1β and 15-deoxy-Δ12,14-prostaglandin J2 regulate the temporal synthesis of matrix metalloproteinase-9 in sheared chondrocytes.Epithelial-mesenchymal transition and fibrosis are mutually exclusive reponses in shear-activated proximal tubular epithelial cells.Mesothelin binding to CA125/MUC16 promotes pancreatic cancer cell motility and invasion via MMP-7 activation.Notch4-dependent antagonism of canonical TGF-β1 signaling defines unique temporal fluctuations of SMAD3 activity in sheared proximal tubular epithelial cells.Prostaglandin D2 toxicity in primary neurons is mediated through its bioactive cyclopentenone metabolites.Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition.Sialyl Lewisx-dependent binding of human monocyte-derived dendritic cells to selectins.Prostaglandins antagonistically control Bax activation during apoptosis Prostaglandins and rheumatoid arthritis.

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Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases

http://www.wikidata.org/entity/Q33926052

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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Prostaglandin (PG)D(2) and 15- ...... egulation of polo-like kinases

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A Kontrogianni-Konstantopoulos

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F Zhu

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K Konstantopoulos

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Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3

CITED2-mediated regulation of MMP-1 and MMP-13 in human chondrocytes under flow shear

15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils

Mapping of picoeucaryotes in marine ecosystems with quantitative PCR of the 18S rRNA gene.

Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis.

15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis.

Shear-induced cyclooxygenase-2 via a JNK2/c-Jun-dependent pathway regulates prostaglandin receptor expression in chondrocytic cells.

Prostaglandin E2 stimulates insulin-like growth factor binding protein-4 expression and synthesis in cultured human articular chondrocytes: possible mediation by Ca(++)-calmodulin regulated processes.

Molecular mechanism of endothelial growth arrest by laminar shear stress.

Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes.

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10.1038/CDD.2010.13

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