Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria - Wikidata - awgldk - TriplyDB

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria

http://www.wikidata.org/entity/Q33927528

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Splenic Macrophage Subsets and Their Function during Blood-Borne Infections Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria.3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1β interferes with mature IL-1β signaling Inflammasomes in host response to protozoan parasites.Hemolysis-induced lethality involves inflammasome activation by heme Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection.Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation DNA-sensing inflammasomes: regulation of bacterial host defense and the gut microbiota.Commensal Bacteria-Induced Inflammasome Activation in Mouse and Human Macrophages Is Dependent on Potassium Efflux but Does Not Require Phagocytosis or Bacterial Viability.IL-1 signaling inhibits Trichophyton rubrum conidia development and modulates the IL-17 response in vivo.STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria.DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity NLR proteins and parasitic disease.Worldwide malaria incidence and cancer mortality are inversely associated.NLR-regulated pathways in cancer: opportunities and obstacles for therapeutic interventions.Cytosolic nucleic acid sensors and innate immune regulation.Cytokines and Chemokines in Cerebral Malaria Pathogenesis.Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria.Identification of Aim2 as a sensor for DNA vaccines.How inflammasomes inform adaptive immunity.Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria.Aminated nanomicelles as a designer vaccine adjuvant to trigger inflammasomes and multiple arms of the innate immune response in lymph nodes.Deviant Behavior: Tick-Borne Pathogens and Inflammasome Signaling.The AIM2 inflammasome: Sensor of pathogens and cellular perturbations.The Major Chromoblastomycosis Etiologic Agent Fonsecaea pedrosoi Activates the NLRP3 Inflammasome.A noncanonical function of cGAMP in inflammasome priming and activation.Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.Cutting Edge: Plasmodium falciparum Induces Trained Innate Immunity.cGAMP: A tale of two signals.Integrative Approaches to Understand the Mastery in Manipulation of Host Cytokine Networks by Protozoan Parasites with Emphasis on Plasmodium and Leishmania Species.The Emerging Role of Pattern Recognition Receptors in the Pathogenesis of Malaria.Asymptomatic Plasmodium vivax parasitaemia in the low-transmission setting: the role for a population-based transmission-blocking vaccine for malaria elimination.Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation.Elevated plasma abscisic acid is associated with asymptomatic falciparum malaria and with IgG-/caspase-1-dependent immunity in Plasmodium yoelii-infected mice.Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria Effects of type I interferons in malaria Daily Rhythms of TNFα Expression and Food Intake Regulate Synchrony of Plasmodium Stages with the Host Circadian Cycle

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P2860

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria

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2014 nî lūn-bûn

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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2014 թվականի հունվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Dual engagement of the NLRP3 a ...... emozoin and DNA during malaria

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J.CELREP.2013.12.014

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Dual engagement of the NLRP3 a ...... emozoin and DNA during malaria

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Andrea Stutz

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Douglas T Golenbock

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Eicke Latz

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Jennie Chan

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Katherine A Fitzgerald

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Parisa Kalantari

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Rosane B DeOliveira

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Vijay Rathinam

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P2860

Genome sequence of the human malaria parasite Plasmodium falciparum

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

The global distribution of clinical episodes of Plasmodium falciparum malaria

Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Gout-associated uric acid crystals activate the NALP3 inflammasome

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

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196-210

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10.1016/J.CELREP.2013.12.014

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1

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6

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Yolanda Corbett

Ricardo Tostes Gazzinelli

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2014-01-02T00:00:00Z

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259586719

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24388751

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4105362

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