PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
about
The insulin-like growth factor system in cancerMicroenvironmental Targets in SarcomaTissue plasminogen activator is a potent activator of PDGF-CCProtein disorder in the human diseasome: unfoldomics of human genetic diseases.Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma.Is There a Predisposition Gene for Ewing's Sarcoma?Ewing Sarcoma, an enigmatic malignancy of likely progenitor cell origin, driven by transcription factor oncogenic fusions.Dominant negative PDGF-C inhibits growth of Ewing family tumor cell lines.VEGF-independent angiogenic pathways induced by PDGF-C.New therapeutic targets in soft tissue sarcoma.Biology of EWS/ETS fusions in Ewing's family tumors.Copy Number Alterations and Methylation in Ewing's Sarcoma.PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteinsEwing's sarcoma: diagnostic, prognostic, and therapeutic implications of molecular abnormalities.Platelet-derived growth factor-C (PDGF-C) activation by serine proteases: implications for breast cancer progressionThe Association of Serum IL-33 and sST2 with Breast CancerEwing's sarcoma oncoprotein EWS-FLI1: the perfect target without a therapeutic agent.Molecular pathogenesis of Ewing sarcoma: new therapeutic and transcriptional targets.A molecular function map of Ewing's sarcoma.Novel targeted therapies in the treatment of soft-tissue sarcomas.The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors.Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1.Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells.KIT expression and methylation in medulloblastoma and PNET cell lines and tumors.Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors.The EWS/FLI1 oncogenic transcription factor deregulates GLI1.Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer.Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation.DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis.Pathology of Ewing's sarcoma/PNET: Current opinion and emerging concepts.Proliferation of Ewing sarcoma cell lines is suppressed by the receptor tyrosine kinase inhibitors gefitinib and vandetanibErythroblast transformation by FLI-1 depends upon its specific DNA binding and transcriptional activation properties.Homotypic and heterotypic interactions of EWS, FLI1 and their oncogenic fusion protein.
P2860
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P2860
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
@ast
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
@en
type
label
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
@ast
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
@en
prefLabel
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
@ast
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
@en
P2860
P356
P1433
P1476
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204133
P407
P577
2001-02-01T00:00:00Z
P5875
P6179
1052258035