Yeast Upf proteins required for RNA surveillance affect global expression of the yeast transcriptome.
about
An unappreciated role for RNA surveillanceNoisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decayCloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance proteinDHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegansNovel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexesNonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knifeItt1p, a novel protein inhibiting translation termination in Saccharomyces cerevisiaeNonsense-mediated mRNA decay: novel mechanistic insights and biological impactNuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeastPhysiological basis of copper tolerance of Saccharomyces cerevisiae nonsense-mediated mRNA decay mutants.SRC1: an intron-containing yeast gene involved in sister chromatid segregation.Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3pOverexpression of Upf1p compensates for mitochondrial splicing deficiency independently of its role in mRNA surveillance.Translational regulator RpL10p/Grc5p interacts physically and functionally with Sed1p, a dynamic component of the yeast cell surface.Ebs1p, a negative regulator of gene expression controlled by the Upf proteins in the yeast Saccharomyces cerevisiae.Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough.Transcript selection and the recruitment of mRNA decay factors for NMD in Saccharomyces cerevisiaeNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryOrganizing principles of mammalian nonsense-mediated mRNA decayEvidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathwayThe RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNAImpact of nonsense-mediated mRNA decay on the global expression profile of budding yeast.Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae.UPF1, a conserved nonsense-mediated mRNA decay factor, regulates cyst wall protein transcripts in Giardia lamblia.High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection.Cryptic transcription mediates repression of subtelomeric metal homeostasis genes.Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs.Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiaeLoss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1Gene set coregulated by the Saccharomyces cerevisiae nonsense-mediated mRNA decay pathway.Genome-wide analysis of mRNA stability using transcription inhibitors and microarrays reveals posttranscriptional control of ribosome biogenesis factors.Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets.New insights into the incorporation of natural suppressor tRNAs at stop codons in Saccharomyces cerevisiaemRNAs encoding telomerase components and regulators are controlled by UPF genes in Saccharomyces cerevisiaeYeast frameshift suppressor mutations in the genes coding for transcription factor Mbf1p and ribosomal protein S3: evidence for autoregulation of S3 synthesisNonsense-mediated mRNA decay controls the changes in yeast ribosomal protein pre-mRNAs levels upon osmotic stressTranscriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability.RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish.Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional response to oxidative stress in fission yeast
P2860
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P2860
Yeast Upf proteins required for RNA surveillance affect global expression of the yeast transcriptome.
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Yeast Upf proteins required fo ...... on of the yeast transcriptome.
@ast
Yeast Upf proteins required fo ...... on of the yeast transcriptome.
@en
type
label
Yeast Upf proteins required fo ...... on of the yeast transcriptome.
@ast
Yeast Upf proteins required fo ...... on of the yeast transcriptome.
@en
prefLabel
Yeast Upf proteins required fo ...... on of the yeast transcriptome.
@ast
Yeast Upf proteins required fo ...... on of the yeast transcriptome.
@en
P2860
P356
P1476
Yeast Upf proteins required fo ...... on of the yeast transcriptome.
@en
P2093
M J Lelivelt
M R Culbertson
P2860
P304
P356
10.1128/MCB.19.10.6710
P407
P577
1999-10-01T00:00:00Z