Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.

Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.

Item
http://www.wikidata.org/entity/Q33966887
Target DNA structure plays a critical role in RAG transposition.Rag-1 mutations associated with B-cell-negative scid dissociate the nicking and transesterification steps of V(D)J recombination.The RAG proteins in V(D)J recombination: more than just a nuclease.Targeted transposition by the V(D)J recombinase.Mutational analysis of all conserved basic amino acids in RAG-1 reveals catalytic, step arrest, and joining-deficient mutants in the V(D)J recombinaseIdentification and characterization of a gain-of-function RAG-1 mutant.Requirements for DNA hairpin formation by RAG1/2Understanding how the V(D)J recombinase catalyzes transesterification: distinctions between DNA cleavage and transposition.A RAG1 mutation found in Omenn syndrome causes coding flank hypersensitivity: a novel mechanism for antigen receptor repertoire restrictionAn amphioxus RAG1-like DNA fragment encodes a functional central domain of vertebrate core RAG1.V(D)J Recombination: Mechanism, Errors, and Fidelity.RAG-heptamer interaction in the synaptic complex is a crucial biochemical checkpoint for the 12/23 recombination rule.Role of DNA end distortion in catalysis by avian sarcoma virus integrase.Amino acid residues in Rag1 crucial for DNA hairpin formation.
P2860

Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.

Item
http://www.wikidata.org/entity/Q33966887
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.
@ast
Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.
@en
type
label
Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.
@ast
Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.
@en
prefLabel
Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.
@ast
Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.
@en
P2093
P2860
P304
P31
P356
10.1128/MCB.21.2.459-466.2001
P407
P433
P478
P577
P698
P932