Bmi1 regulates mitochondrial function and the DNA damage response pathway - Wikidata - awgldk - TriplyDB

Bmi1 regulates mitochondrial function and the DNA damage response pathway

Bmi1 regulates mitochondrial function and the DNA damage response pathway

http://www.wikidata.org/entity/Q34017298

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UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity BRCA1 is a negative modulator of the PRC2 complex BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair BMI1: A Biomarker of Hematologic Malignancies Radioresistance of Brain Tumors Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work Reactive Oxygen Species in Mesenchymal Stem Cell Aging: Implication to Lung Diseases To breathe or not to breathe: the haematopoietic stem/progenitor cells dilemma Emerging role of cancer stem cells in the biology and treatment of ovarian cancer: basic knowledge and therapeutic possibilities for an innovative approach Redox regulation of stem/progenitor cells and bone marrow niche Maintaining tissue homeostasis: dynamic control of somatic stem cell activity Genetic regulation of thymocyte progenitor aging Axis of ageing: telomeres, p53 and mitochondria Reactive oxygen species adversely impacts bone marrow microenvironment in diabetes Molecular mechanism of extrinsic factors affecting anti-aging of stem cells Wnt activation protects against neomycin-induced hair cell damage in the mouse cochlea TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells Linking functional decline of telomeres, mitochondria and stem cells during ageing Mitochondria-ros crosstalk in the control of cell death and aging Bioenergetic profiling of zebrafish embryonic development Ambient oxygen promotes tumorigenesis A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1 Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha Expression of lactoperoxidase in differentiated mouse colon epithelial cells Reduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitro ROS function in redox signaling and oxidative stress Signal transduction by reactive oxygen species Bmi1 regulates auditory hair cell survival by maintaining redox balance.The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.RUG3 and ATM synergistically regulate the alternative splicing of mitochondrial nad2 and the DNA damage response in Arabidopsis thaliana.MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence.Intestinal stem cells and their roles during mucosal injury and repair.MUC1-C activates BMI1 in human cancer cells.Purinergic P2Y₁₄ receptor modulates stress-induced hematopoietic stem/progenitor cell senescence

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P2860

Bmi1 regulates mitochondrial function and the DNA damage response pathway

http://www.wikidata.org/entity/Q34017298

description

2009 nî lūn-bûn

@nan

2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

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2009年论文

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name

Bmi1 regulates mitochondrial function and the DNA damage response pathway

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

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type

label

Bmi1 regulates mitochondrial function and the DNA damage response pathway

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

@en

Bmi1 regulates mitochondrial function and the DNA damage response pathway

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

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Bong-Hyun Ahn

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Celia Quijano

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Chu-Xia Deng

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Haoqian Chen

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Hongjun Liu

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Ilsa I Rovira

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In Hye Lee

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Jichun Chen

http://www.w3.org/2001/XMLSchema#string

Jie Liu

http://www.w3.org/2001/XMLSchema#string

Keyvan Keyvanfar

http://www.w3.org/2001/XMLSchema#string

P2860

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways.

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

p16INK4a induces an age-dependent decline in islet regenerative potential

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

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10.1038/NATURE08040

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1039237755

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