Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia.
about
PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phaseNitric oxide and peroxynitrite in health and diseasePoly(ADP-ribose) polymerase-1 inhibition in brain endothelium protects the blood-brain barrier under physiologic and neuroinflammatory conditions.Chemokine-cytokine cross-talk. The ELR+ CXC chemokine LIX (CXCL5) amplifies a proinflammatory cytokine response via a phosphatidylinositol 3-kinase-NF-kappa B pathwayPARP-1 Inhibition Is Neuroprotective in the R6/2 Mouse Model of Huntington's DiseaseAn integrated perspective on diabetic, alcoholic, and drug-induced neuropathy, etiology, and treatment in the US.Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cellsPoly(ADP-ribose) polymerase-1 regulates vimentin expression in lung cancer cells.Transcriptional regulation by poly(ADP-ribose) polymerase-1 during T cell activation.Diabetic neuropathy: mechanisms to managementTargeting microglial activation in stroke therapy: pharmacological tools and gender effects.Regulation of necrotic cell death: p53, PARP1 and cyclophilin D-overlapping pathways of regulated necrosis?New therapeutic and biomarker discovery for peripheral diabetic neuropathy: PARP inhibitor, nitrotyrosine, and tumor necrosis factor-{alpha}PARP1 enhances inflammatory cytokine expression by alteration of promoter chromatin structure in microglia.Pathophysiology of cisplatin-induced acute kidney injury.Mechanisms of vascular aging: new perspectives.Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death.Development of synthetic lethality anticancer therapeutics.PARP-1 inhibitors DPQ and PJ-34 negatively modulate proinflammatory commitment of human glioblastoma cells.Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease.Absence of poly(ADP-ribose)polymerase-1 alters nuclear factor-kappa B activation and gene expression of apoptosis regulators after reperfusion injury.Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.Inducible nitric oxide synthase gene deficiency counteracts multiple manifestations of peripheral neuropathy in a streptozotocin-induced mouse model of diabetes.Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat modelPARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathyPARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function.Partial protection against collagen antibody-induced arthritis in PARP-1 deficient mice.Anti-inflammatory effects of PJ34, a poly(ADP-ribose) polymerase inhibitor, in transient focal cerebral ischemia in miceFine tuning the transcriptional regulation of the CXCL1 chemokineFibroblast growth factor regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway.PARP1 activation/expression modulates regional-specific neuronal and glial responses to seizure in a hemodynamic-independent manner.Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells.Poly(ADP-ribose)polymerase inhibition counteracts renal hypertrophy and multiple manifestations of peripheral neuropathy in diabetic Akita micePoly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors.Histone ADP-ribosylation facilitates gene transcription by directly remodeling nucleosomesNF-κB transcriptional activation by TNFα requires phospholipase C, extracellular signal-regulated kinase 2 and poly(ADP-ribose) polymerase-1Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitorsAldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells.Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy
P2860
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P2860
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Poly(ADP-ribose) polymerase-1 ...... iated gene expression in glia.
@ast
Poly(ADP-ribose) polymerase-1 ...... iated gene expression in glia.
@en
type
label
Poly(ADP-ribose) polymerase-1 ...... iated gene expression in glia.
@ast
Poly(ADP-ribose) polymerase-1 ...... iated gene expression in glia.
@en
prefLabel
Poly(ADP-ribose) polymerase-1 ...... iated gene expression in glia.
@ast
Poly(ADP-ribose) polymerase-1 ...... iated gene expression in glia.
@en
P2860
P356
P1476
Poly(ADP-ribose) polymerase-1 ...... iated gene expression in glia.
@en
P2093
Hyo Chol Ha
Lynda D Hester
P2860
P304
P356
10.1073/PNAS.052712399
P407
P577
2002-02-19T00:00:00Z