Theoretical models of the ion channel structure of amyloid beta-protein.
about
The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motifFunctional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesisSolution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domainModels of membrane-bound Alzheimer's Abeta peptide assembliesSynthetic multifunctional pores: lessons from rigid-rod beta-barrels.Transbilayer pores formed by beta-barrels: molecular modeling of pore structures and properties.Role of endocytic inhibitory drugs on internalization of amyloidogenic light chains by cardiac fibroblasts.Calcium signaling and amyloid toxicity in Alzheimer disease.Amyloid-beta-induced ion flux in artificial lipid bilayers and neuronal cells: resolving a controversyExpression of human beta-amyloid peptide in transgenic Caenorhabditis elegansAmyloid ion channels: a common structural link for protein-misfolding diseaseAlzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons.Displacement currents associated with the insertion of Alzheimer disease amyloid beta-peptide into planar bilayer membranesModeling amyloid beta-peptide insertion into lipid bilayersPhysicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.Ion channel formation and membrane-linked pathologies of misfolded hydrophobic proteins: the role of dangerous unchaperoned molecules.Membrane Incorporation, Channel Formation, and Disruption of Calcium Homeostasis by Alzheimer's β-Amyloid Protein.Small molecule blockers of the Alzheimer Abeta calcium channel potently protect neurons from Abeta cytotoxicity.The amyloid beta ion channel hypothesis of Alzheimer's disease.Medicinal chemistry approaches for the treatment and prevention of Alzheimer's disease.Calcitonin forms oligomeric pore-like structures in lipid membranes.Single-channel Ca(2+) imaging implicates Aβ1-42 amyloid pores in Alzheimer's disease pathologyThe slowly aggregating salmon Calcitonin: a useful tool for the study of the amyloid oligomers structure and activity.Nanoimaging for protein misfolding and related diseases.Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm.Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channelsCalcium dyshomeostasis and neurotoxicity of Alzheimer's beta-amyloid protein.The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders.Zn2+ interaction with Alzheimer amyloid beta protein calcium channelsOxidative stress and cell membranes in the pathogenesis of Alzheimer's disease.Observation of molecular inhibition and binding structures of amyloid peptides.Disruption of zinc homeostasis and the pathogenesis of senile dementia.Lipid composition influences the release of Alzheimer's amyloid β-peptide from membranes.Ion Channel Formation by Amyloid-β42 Oligomers but Not Amyloid-β40 in Cellular Membranes.Cross talk between neurometals and amyloidogenic proteins at the synapse and the pathogenesis of neurodegenerative diseases.Alzheimer Aβ peptide interactions with lipid membranes: fibrils, oligomers and polymorphic amyloid channels.Effect of sterols on beta-amyloid peptide (AbetaP 1-40) channel formation and their properties in planar lipid membranes.Molecular dynamics simulation of amyloid beta dimer formation.The toxicity in vitro of beta-amyloid protein.Retardation of Abeta fibril formation by phospholipid vesicles depends on membrane phase behavior.
P2860
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P2860
Theoretical models of the ion channel structure of amyloid beta-protein.
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
name
Theoretical models of the ion channel structure of amyloid beta-protein.
@ast
Theoretical models of the ion channel structure of amyloid beta-protein.
@en
Theoretical models of the ion channel structure of amyloid beta-protein.
@nl
type
label
Theoretical models of the ion channel structure of amyloid beta-protein.
@ast
Theoretical models of the ion channel structure of amyloid beta-protein.
@en
Theoretical models of the ion channel structure of amyloid beta-protein.
@nl
prefLabel
Theoretical models of the ion channel structure of amyloid beta-protein.
@ast
Theoretical models of the ion channel structure of amyloid beta-protein.
@en
Theoretical models of the ion channel structure of amyloid beta-protein.
@nl
P2093
P2860
P1433
P1476
Theoretical models of the ion channel structure of amyloid beta-protein.
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(94)80717-9
P407
P577
1994-12-01T00:00:00Z