The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells.
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NF-kB inhibitor blocks B cell development at two checkpointsUnexpected functions of nuclear factor-κB during germinal center B-cell development: implications for lymphomagenesisTo be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosisThe c-Rel transcription factor and B-cell proliferation: a deal with the devilIkappaB kinase signaling is essential for maintenance of mature B cellsSiglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activationTRAF6 is required for generation of the B-1a B cell compartment as well as T cell-dependent and -independent humoral immune responses.c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells.Roles of the NF-kappaB pathway in lymphocyte development and function.Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice.Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells.IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen.Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits.B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in IκBNS.Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways.Circuitry of nuclear factor kappaB signaling.FlowMax: A Computational Tool for Maximum Likelihood Deconvolution of CFSE Time Courses.Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.A multi-scale approach reveals that NF-κB cRel enforces a B-cell decision to divide.MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.Nfkb1 activation by the E26 transformation-specific transcription factors PU.1 and Spi-B promotes Toll-like receptor-mediated splenic B cell proliferation.Gastroenteritis in NF-kappaB-deficient mice is produced with wild-type Camplyobacter jejuni but not with C. jejuni lacking cytolethal distending toxin despite persistent colonization with both strains.The c-Rel Transcription Factor in Development and Disease.Formation of B-1 B cells from neonatal B-1 transitional cells exhibits NF-κB redundancy.The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory propertiesc-Rel plays a key role in deficient activation of B cells from a non-X-linked hyper-IgM patient.The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver.NF-kappaB1 and c-Rel cooperate to promote the survival of TLR4-activated B cells by neutralizing Bim via distinct mechanisms.Genes, pathways and checkpoints in lymphocyte development and homeostasis.Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo functionNFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cellsThe Paracaspase MALT1.The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms.NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.NF-kappaB p50 plays distinct roles in the establishment and control of murine gammaherpesvirus 68 latency.A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes.TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40.Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma.Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation.
P2860
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P2860
The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells.
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The combined absence of NF-kap ...... and function of mature cells.
@ast
The combined absence of NF-kap ...... and function of mature cells.
@en
The combined absence of NF-kap ...... and function of mature cells.
@nl
type
label
The combined absence of NF-kap ...... and function of mature cells.
@ast
The combined absence of NF-kap ...... and function of mature cells.
@en
The combined absence of NF-kap ...... and function of mature cells.
@nl
prefLabel
The combined absence of NF-kap ...... and function of mature cells.
@ast
The combined absence of NF-kap ...... and function of mature cells.
@en
The combined absence of NF-kap ...... and function of mature cells.
@nl
P2093
P2860
P50
P356
P1476
The combined absence of NF-kap ...... and function of mature cells.
@en
P2093
David Baltimore
Raelene J Grumont
Raffi Gugasyan
Steve Gerondakis
Thomas Pohl
William Sha
P2860
P304
P356
10.1073/PNAS.072071599
P407
P577
2002-04-01T00:00:00Z