Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists.
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Novel NMDA receptor modulators: an updateFunctional insights from glutamate receptor ion channel structuresStructural Insights into Competitive Antagonism in NMDA ReceptorsFrom molecular phylogeny towards differentiating pharmacology for NMDA receptor subtypesGlutamate receptor ion channels: structure, regulation, and functionConantokins derived from the Asprella clade impart conRl-B, an N-methyl d-aspartate receptor antagonist with a unique selectivity profile for NR2B subunits.Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator.Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulatorsNew advances in NMDA receptor pharmacology.Piperazine-2,3-dicarboxylic acid derivatives as dual antagonists of NMDA and GluK1-containing kainate receptorsStructure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid.Molecular pharmacology of human NMDA receptorsAn Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors.Subunit-selective allosteric inhibition of glycine binding to NMDA receptorsCoumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors.Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators.Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-oneStructure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists.NMDA Receptors Containing the GluN2D Subunit Control Neuronal Function in the Subthalamic Nucleus.Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbersSynthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptorsInhibition of GluN2A-containing N-methyl-D-aspartate receptors by 2-naphthoic acidAllosteric modulators for the treatment of schizophrenia: targeting glutamatergic networksNovel N-methyl-D-aspartate receptor antagonists: a review of compounds patented since 2006.Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulatorsInfluence of GluN2 subunit identity on NMDA receptor function.Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators.Structural and mechanistic determinants of a novel site for noncompetitive inhibition of GluN2D-containing NMDA receptors.The bioactive protein-ligand conformation of GluN2C-selective positive allosteric modulators bound to the NMDA receptor.A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons.NMDA Receptors in the Central Nervous System.The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.Developmental Changes of Synaptic and Extrasynaptic NMDA Receptor Expression in Rat Cerebellar Neurons In Vitro.Vesicular glutamate release from central axons contributes to myelin damage.Altered Synaptic and Extrasynaptic NMDA Receptor Properties in Substantia Nigra Dopaminergic Neurons From Mice Lacking the GluN2D SubunitA structurally derived model of subunit-dependent NMDA receptor function
P2860
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P2860
Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@ast
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@en
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@nl
type
label
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@ast
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@en
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@nl
prefLabel
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@ast
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@en
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@nl
P2093
P2860
P356
P1476
Quinazolin-4-one derivatives: ...... spartate receptor antagonists.
@en
P2093
Cara A Mosley
Dennis C Liotta
Hans Bräuner-Osborne
Karen T Andersen
Kasper B Hansen
Kimberly M Vellano
Praseeda Mullasseril
Stephen F Traynelis
Timothy M Acker
P2860
P304
P356
10.1021/JM100027P
P407
P577
2010-08-01T00:00:00Z