The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells.

The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells.

Item
http://www.wikidata.org/entity/Q34066703
The multifaceted functions of C/EBPα in normal and malignant haematopoiesis.The +37 kb Cebpa Enhancer Is Critical for Cebpa Myeloid Gene Expression and Contains Functional Sites that Bind SCL, GATA2, C/EBPα, PU.1, and Additional Ets Factors.In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis.Runx1 Phosphorylation by Src Increases Trans-activation via Augmented Stability, Reduced Histone Deacetylase (HDAC) Binding, and Increased DNA Affinity, and Activated Runx1 Favors GranulopoiesisGenome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia.C/EBPα in normal and malignant myelopoiesis.The analysis of novel distal Cebpa enhancers and silencers using a transcriptional model reveals the complex regulatory logic of hematopoietic lineage specification.RUNX1 and CBFβ Mutations and Activities of Their Wild-Type Alleles in AML.
P2860

The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells.

Item
http://www.wikidata.org/entity/Q34066703
description
2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@ast
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@en
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@nl
type
label
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@ast
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@en
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@nl
prefLabel
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@ast
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@en
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
The Cebpa +37-kb enhancer dire ...... term hematopoietic stem cells.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932