Mutations within the P-loop of Kir6.2 modulate the intraburst kinetics of the ATP-sensitive potassium channel.
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Structural basis for the coupling between activation and inactivation gates in K(+) channelsStructural mechanism of C-type inactivation in K(+) channelsHyperinsulinemic Hypoglycemia - The Molecular MechanismsNeuroprotective role of ATP-sensitive potassium channels in cerebral ischemiaOn the structural basis of modal gating behavior in K+ channelsA novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channelsNovel nucleotide-binding sites in ATP-sensitive potassium channels formed at gating interfaces.Molecular determinants of gating at the potassium-channel selectivity filter.Molecular driving forces determining potassium channel slow inactivation.The pore helix is involved in stabilizing the open state of inwardly rectifying K+ channels.Concerted gating mechanism underlying KATP channel inhibition by ATP.A ring of negative charges in the intracellular vestibule of Kir2.1 channel modulates K+ permeation.The ligand-sensitive gate of a potassium channel lies close to the selectivity filter.Conformational dynamics of the KcsA potassium channel governs gating properties.A Kir6.2 pore mutation causes inactivation of ATP-sensitive potassium channels by disrupting PIP2-dependent gating.A multipoint hydrogen-bond network underlying KcsA C-type inactivation.Gating mechanism of KATP channels: function fits form.Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conductionGating and inward rectifying properties of the MthK K+ channel with and without the gating ring.Pore structure influences gating properties of the T-type Ca2+ channel alpha1GFrom molecule to malady.Electrostatics in the cytoplasmic pore produce intrinsic inward rectification in kir2.1 channels.Emergence of ion channel modal gating from independent subunit kinetics.Changes in negative charge at the luminal mouth of the pore alter ion handling and gating in the cardiac ryanodine-receptor.Proton inhibition of unitary currents of vanilloid receptors.Risk loci for type 2 diabetes - quo vadis?Aromatic-aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process.Current understanding of K ATP channels in neonatal diseases: focus on insulin secretion disorders.Differential regulation of the InsP₃ receptor type-1 and -2 single channel properties by InsP₃, Ca²⁺ and ATP.Tl+-induced micros gating of current indicates instability of the MaxiK selectivity filter as caused by ion/pore interaction.Saturation and microsecond gating of current indicate depletion-induced instability of the MaxiK selectivity filter.K(+) versus Na(+) ions in a K channel selectivity filter: a simulation study.Filter flexibility in a mammalian K channel: models and simulations of Kir6.2 mutants.Filter flexibility and distortion in a bacterial inward rectifier K+ channel: simulation studies of KirBac1.1.Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.Base of pore loop is important for rectification, activation, permeation, and block of Kir3.1/Kir3.4.Control of Kir channel gating by cytoplasmic domain interface interactionsThe selectivity filter may act as the agonist-activated gate in the G protein-activated Kir3.1/Kir3.4 K+ channel.Protein kinase C mediated pH(i)-regulation of ROMK1 channels via a phosphatidylinositol-4,5-bisphosphate-dependent mechanism.Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity.
P2860
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P2860
Mutations within the P-loop of Kir6.2 modulate the intraburst kinetics of the ATP-sensitive potassium channel.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Mutations within the P-loop of ...... P-sensitive potassium channel.
@ast
Mutations within the P-loop of ...... P-sensitive potassium channel.
@en
Mutations within the P-loop of ...... P-sensitive potassium channel.
@nl
type
label
Mutations within the P-loop of ...... P-sensitive potassium channel.
@ast
Mutations within the P-loop of ...... P-sensitive potassium channel.
@en
Mutations within the P-loop of ...... P-sensitive potassium channel.
@nl
prefLabel
Mutations within the P-loop of ...... P-sensitive potassium channel.
@ast
Mutations within the P-loop of ...... P-sensitive potassium channel.
@en
Mutations within the P-loop of ...... P-sensitive potassium channel.
@nl
P2093
P2860
P356
P1476
Mutations within the P-loop of ...... P-sensitive potassium channel.
@en
P2093
P2860
Homology modeling and molecular dynamics simulation studies of an inward rectifier potassium channel
Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor
P304
P356
10.1085/JGP.118.4.341
P577
2001-10-01T00:00:00Z