Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.
about
Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channelsThe Nucleotide-Binding Sites of SUR1: A Mechanistic ModelMolecular action of sulphonylureas on KATP channels: a real partnership between drugs and nucleotidesMutations of the same conserved glutamate residue in NBD2 of the sulfonylurea receptor 1 subunit of the KATP channel can result in either hyperinsulinism or neonatal diabetesElectrophysiology properties of voltage-gated potassium channels in rat peritoneal macrophagesThe unusual stoichiometry of ADP activation of the KATP channel.Metabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells.The shifting landscape of KATP channelopathies and the need for 'sharper' therapeutics.The Pancreatic β-Cell: A Bioenergetic Perspective.Neonatal Diabetes and the KATP Channel: From Mutation to Therapy.A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening.Reinterpreting the action of ATP analogs on K(ATP) channels.Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic studyMolecular mechanism of sulphonylurea block of K(ATP) channels carrying mutations that impair ATP inhibition and cause neonatal diabetes.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.Calcium dynamics control K-ATP channel-mediated bursting in substantia nigra dopamine neurons: a combined experimental and modeling study.Molecular structure of human KATP in complex with ATP and ADP.Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels.Binding of sulphonylureas to plasma proteins - A KATP channel perspective.Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
P2860
Q26744692-E5D1C50A-3382-4C33-BA1D-582CF5AAE657Q26774807-04D8A384-964F-442B-8632-EA9370636771Q26777728-10A75216-AE3C-46DF-8666-C4B78FD9A6CDQ35043410-456315B4-CC3A-4EFC-B345-A728F349582DQ36720998-4EC97919-595E-4988-B275-777200D7EBFEQ37522353-3473C442-C1F7-463D-AA66-8DC46512B820Q38712872-597F60AB-B67B-4015-99AB-B7180AE6D22DQ38869442-12B88B69-9839-4E5B-9E3F-0BD1E5EE89DEQ38943061-6E6266AA-A0E5-409F-A528-9DB014C87436Q39163344-0058B008-7054-4D97-9348-1A6708878E77Q41247700-CA482183-879C-4C3F-A609-515AD413B953Q41469020-3F67B996-E536-4544-82AC-B70D146BAAFFQ42089444-E6B35070-5CE0-4E27-AE90-3F7BC3EE2F5DQ42126795-AAF55C9B-42EB-43C2-964F-462CF9D693DCQ47322426-A760C19C-1961-4D50-8B59-F4FA7D03025BQ47661489-C9538018-B5D9-42AD-AD34-593E0BBAD0F5Q48332432-E4184D86-BFE4-48A9-8F60-3D5462E42095Q52312167-5095D837-1CFA-4EF9-AD6C-2B3EEDF78458Q55261423-CD3309E0-73A9-452F-8C86-E5233B81B44DQ55283497-E12F6321-E180-417F-B2E3-937EE10A13B1
P2860
Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.
@en
type
label
Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.
@en
prefLabel
Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.
@en
P2860
P356
P1476
Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.
@en
P2093
Frances M Ashcroft
Peter Proks
P2860
P304
P356
10.1085/JGP.201010475
P50
P577
2010-10-01T00:00:00Z