Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins.
about
Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesCarboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTORThe Role of G-Protein-Coupled Receptor Proteolysis Site Cleavage of Polycystin-1 in Renal Physiology and Polycystic Kidney DiseaseRole of the Polycystins in Cell Migration, Polarity, and Tissue MorphogenesisAccessory proteins for heterotrimeric G-proteins in the kidneyPolycystin-1 cleavage and the regulation of transcriptional pathwaysMechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminusSystems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney diseaseTAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complexNative polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epitheliaPolycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2.A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.Receptor protein tyrosine phosphatases are novel components of a polycystin complexPolycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway.Mechanisms of p53-mediated repression of the human polycystic kidney disease-1 promoterImplications of non-canonical G-protein signaling for the immune systemActivator of G protein signaling 3 promotes epithelial cell proliferation in PKD.The cell biology of polycystic kidney diseaseProtein phosphatase-1α interacts with and dephosphorylates polycystin-1MAP/ERK kinase kinase 1 (MEKK1) mediates transcriptional repression by interacting with polycystic kidney disease-1 (PKD1) promoter-bound p53 tumor suppressor proteinKidney: polycystic kidney disease.Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway.Effect of PKD1 gene missense mutations on polycystin-1 membrane topogenesis.New insights into ciliary function: kidney cysts and photoreceptors.Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.Cilium, centrosome and cell cycle regulation in polycystic kidney disease.Inactivation of integrin-β1 prevents the development of polycystic kidney disease after the loss of polycystin-1.Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice.Autosomal dominant polycystic kidney disease (ADPKD, MIM 173900, PKD1 and PKD2 genes, protein products known as polycystin-1 and polycystin-2).Regulation of Polycystin-1 Function by Calmodulin Binding.G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease.Diagnosis, pathogenesis, and treatment prospects in cystic kidney disease.Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.Infused Fc-tagged beta-glucuronidase crosses the placenta and produces clearance of storage in utero in mucopolysaccharidosis VII mice.Hyperproliferation of PKD1 cystic cells is induced by insulin-like growth factor-1 activation of the Ras/Raf signalling system.Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1.Growth of cranial synchondroses and sutures requires polycystin-1.Characterization of PKD protein-positive exosome-like vesicles.
P2860
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P2860
Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@ast
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@en
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@nl
type
label
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@ast
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@en
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@nl
prefLabel
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@ast
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@en
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@nl
P2093
P356
P1476
Polycystin-1 activation of c-J ...... by heterotrimeric G proteins.
@en
P2093
Anna-Maria Frischauf
Brenda S Magenheimer
Christopher A Zien
James P Calvet
Robin L Maser
Stephen C Parnell
P304
19566-19572
P356
10.1074/JBC.M201875200
P407
P577
2002-03-23T00:00:00Z