Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding - Wikidata - awgldk - TriplyDB

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

http://www.wikidata.org/entity/Q34143246

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Okazaki fragment maturation: nucleases take centre stage Base Excision Repair, a Pathway Regulated by Posttranslational Modifications The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.Interacting partners of FEN1 and its role in the development of anticancer therapeutics.FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer.Tumor necrosis factor (TNF)-α induction of CXCL10 in endothelial cells requires protein arginine methyltransferase 5 (PRMT5)-mediated nuclear factor (NF)-κB p65 methylation.Arginine methylation of hnRNPK negatively modulates apoptosis upon DNA damage through local regulation of phosphorylation.Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection Kinetics of endogenous mouse FEN1 in base excision repair.Functional regulation of FEN1 nuclease and its link to cancer Eukaryotic lagging strand DNA replication employs a multi-pathway mechanism that protects genome integrity Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer Kinase consensus sequences: a breeding ground for crosstalk.Flap endonucleases pass 5'-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5'-ends.Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis.Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression.Sequential posttranslational modifications program FEN1 degradation during cell-cycle progression Flap endonuclease 1.The wonders of flap endonucleases: structure, function, mechanism and regulation.Lysine Acetylation and Succinylation in HeLa Cells and their Essential Roles in Response to UV-induced Stress.PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination.Nuclear PRMT5, cyclin D1 and IL-6 are associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with p16-status.The methylproteome and the intracellular methylation network.BERing the burden of damage: Pathway crosstalk and posttranslational modification of base excision repair proteins regulate DNA damage management.Identification of the PRMT1v1 and PRMT1v2 specific interactomes by quantitative mass spectrometry in breast cancer cells.Protein arginine methylation/demethylation and cancer.The story of protein arginine methylation: characterization, regulation, and function.Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade.Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling.Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage.Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation.Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding Lysine methylation of FEN1 by SET7 is essential for its cellular response to replicative stress.Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.PRMT5-mediated arginine methylation of TDP1 for the repair of topoisomerase I covalent complexes.Protein arginine methylation: an emerging regulator of the cell cycle.JMJD1B Demethylates H4R3me2s and H3K9me2 to Facilitate Gene Expression for Development of Hematopoietic Stem and Progenitor Cells.rs4246215 is targeted by hsa-miR1236 to regulate FEN1 expression but is not associated with Fuchs' endothelial corneal dystrophy

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Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

http://www.wikidata.org/entity/Q34143246

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@ast

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@en

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@nl

type

label

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@ast

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@en

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@nl

prefLabel

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@ast

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@en

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@nl

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P1433

Nature Chemical Biology

P1476

Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding

@en

P2093

Binghui Shen

http://www.w3.org/2001/XMLSchema#string

Hong Xu

http://www.w3.org/2001/XMLSchema#string

Huifang Dai

http://www.w3.org/2001/XMLSchema#string

Li Zheng

http://www.w3.org/2001/XMLSchema#string

Mary Rose Pascua

http://www.w3.org/2001/XMLSchema#string

Mian Zhou

http://www.w3.org/2001/XMLSchema#string

Qin M Chen

http://www.w3.org/2001/XMLSchema#string

Zhigang Guo

http://www.w3.org/2001/XMLSchema#string

P2860

Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms

Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300

JMJD6 is a histone arginine demethylase

Histone deimination antagonizes arginine methylation

Suppression of receptor interacting protein 140 repressive activity by protein arginine methylation

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

Arginine methylation regulates DNA polymerase beta

Regulation of estrogen rapid signaling through arginine methylation by PRMT1

p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

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P304

766-773

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1038/NCHEMBIO.422

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P433

10

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P478

6

http://www.w3.org/2001/XMLSchema#string

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2010-08-22T00:00:00Z

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45800274

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20729856

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

2943039

http://www.w3.org/2001/XMLSchema#string