Homologous recombination resolution defect in werner syndrome. - Wikidata - awgldk - TriplyDB

Homologous recombination resolution defect in werner syndrome.

Homologous recombination resolution defect in werner syndrome.

http://www.wikidata.org/entity/Q34150355

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Physical analyses of E. coli heteroduplex recombination products in vivo: on the prevalence of 5' and 3' patches WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination WRN interacts physically and functionally with the recombination mediator protein RAD52 Werner syndrome protein interacts functionally with translesion DNA polymerases The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1 Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology RNA interference inhibition of Mus81 reduces mitotic recombination in human cells Roles of Werner syndrome protein in protection of genome integrity Model of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromes Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta.Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice RecQ helicases in DNA double strand break repair and telomere maintenance.The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.Evidence that a RecQ helicase slows senescence by resolving recombining telomeres The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation WRN loss induces switching of telomerase-independent mechanisms of telomere elongation RecQ helicases: caretakers of the genome Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast Redundancy of DNA helicases in p53-mediated apoptosis.Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1.Replication protein A stimulates the Werner syndrome protein branch migration activity.WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3 Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation RecQ-dependent death-by-recombination in cells lacking RecG and UvrD Delineation of WRN helicase function with EXO1 in the replicational stress response Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase.WRN participates in translesion synthesis pathway through interaction with NBS1 The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells

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Homologous recombination resolution defect in werner syndrome.

http://www.wikidata.org/entity/Q34150355

description

2002 nî lūn-bûn

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2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Homologous recombination resolution defect in werner syndrome.

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Homologous recombination resolution defect in werner syndrome.

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Homologous recombination resolution defect in werner syndrome.

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type

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Homologous recombination resolution defect in werner syndrome.

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Homologous recombination resolution defect in werner syndrome.

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Homologous recombination resolution defect in werner syndrome.

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Homologous recombination resolution defect in werner syndrome.

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Homologous recombination resolution defect in werner syndrome.

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Homologous recombination resolution defect in werner syndrome.

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MCB.22.20.6971-6978.2002

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Molecular and Cellular Biology

P1476

Homologous recombination resolution defect in werner syndrome.

@en

P2093

Cristina Swanson

http://www.w3.org/2001/XMLSchema#string

Kate Makienko

http://www.w3.org/2001/XMLSchema#string

Mary J Emond

http://www.w3.org/2001/XMLSchema#string

Raymond J Monnat

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Yannick Saintigny

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P2860

The Bloom's syndrome gene product is homologous to RecQ helicases

Mutator phenotype of Werner syndrome is characterized by extensive deletions

Chromosomal stability and the DNA double-stranded break connection

Human Mus81-associated endonuclease cleaves Holliday junctions in vitro

Cancer susceptibility and the functions of BRCA1 and BRCA2

Homologous recombinational repair of DNA ensures mammalian chromosome stability

The importance of repairing stalled replication forks

Positional cloning of the Werner's syndrome gene

Mus81-Eme1 are essential components of a Holliday junction resolvase

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest.

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