Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism
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TRIM5alpha selectively binds a restriction-sensitive retroviral capsidTRIM family proteins: retroviral restriction and antiviral defenceCyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cellsProteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infectionSpecific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factorFunctional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domainsTrim5alpha protein restricts both HIV-1 and murine leukemia virusThe human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activitiesRetrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alphaIn defense of the cell: TRIM5alpha interception of mammalian retrovirusesRestriction of retroviral replication by APOBEC3G/F and TRIM5alphaAll three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restrictionEarly steps of retrovirus replicative cycleConsensus structural models for the amino terminal domain of the retrovirus restriction gene Fv1 and the murine leukaemia virus capsid proteinsIntracellular immunity to HIV-1: newly defined retroviral battles inside infected cells.HIV restriction in quiescent CD4⁺ T cellsStructure of the rhesus monkey TRIM5 PRYSPRY domain, the HIV capsid recognition moduleIdentification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulatorFates of retroviral core components during unrestricted and TRIM5-restricted infectionLv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to IntegrationThe KT Jeang Retrovirology prize 2015: Paul BieniaszCyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1SIV replication in human cellsTRIM5 alpha cytoplasmic bodies are highly dynamic structures.Recruitment and dynamics of proteasome association with rhTRIM5α cytoplasmic complexes during HIV-1 infection.Macaques as model hosts for studies of HIV-1 infectionAbrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells.Identification of synthetic endothelial cell-specific promoters by use of a high-throughput screen.Proteasomal degradation of TRIM5alpha during retrovirus restrictionDemonstration of a novel HIV-1 restriction phenotype from a human T cell lineInducible APOBEC3G-Vif double stable cell line as a high-throughput screening platform to identify antiviral compounds.Novel approaches to inhibiting HIV-1 replication.Transient in vivo beta-globin production after lentiviral gene transfer to hematopoietic stem cells in the nonhuman primateRetrovirus restriction by TRIM5alpha variants from Old World and New World primatesVirus particle core defects caused by mutations in the human immunodeficiency virus capsid N-terminal domainHsp70 interacts with the retroviral restriction factor TRIM5alpha and assists the folding of TRIM5alphaResidues in the murine leukemia virus capsid that differentially govern resistance to mouse Fv1 and human Ref1 restrictions.The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primatesCharacterization of a core fragment of the rhesus monkey TRIM5α protein.Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction
P2860
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P2860
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@ast
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@en
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@nl
type
label
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@ast
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@en
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@nl
prefLabel
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@ast
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@en
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@nl
P2093
P2860
P356
P1476
Cellular inhibitors with Fv1-l ...... immunodeficiency virus tropism
@en
P2093
Heinrich G Gottlinger
Mark A Muesing
Paul D Bieniasz
Simone Cowan
Theodora Hatziioannou
Tshaka Cunningham
P2860
P304
11914-11919
P356
10.1073/PNAS.162299499
P407
P577
2002-08-01T00:00:00Z