Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension. - Wikidata - awgldk - TriplyDB

Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension.

Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension.

http://www.wikidata.org/entity/Q34168724

about

Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregation Identification of two novel components of the human NDC80 kinetochore complex Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension Determinants of conformational dimerization of Mad2 and its inhibition by p31comet Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint Antimitotic drugs in the treatment of cancer Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores.Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments In-silico modeling of the mitotic spindle assembly checkpoint Kinetochore-microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis.Taxol-stabilized microtubules can position the cytokinetic furrow in mammalian cells.Recruitment of Cdc20 to the kinetochore requires BubR1 but not Mad2 in Drosophila melanogaster.Generating chromosome instability through the simultaneous deletion of Mad2 and p53.Mitotic chromosomal instability and cancer: mouse modelling of the human disease.The spindle checkpoint, aneuploidy, and cancer.Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions.Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit.Bipolar orientation of chromosomes in Saccharomyces cerevisiae is monitored by Mad1 and Mad2, but not by Mad3.The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond SUMO modification of DNA topoisomerase II: trying to get a CENse of it all Smurf2 as a novel mitotic regulator: From the spindle assembly checkpoint to tumorigenesis NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpoint Stressing mitosis to death.Hsp70 protects mitotic cells against heat-induced centrosome damage and division abnormalities.Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint"Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2.Determining the position of the cell division plane.Using Photoactivatable GFP to Study Microtubule Dynamics and Chromosome Segregation.Oxidative Stress Delays Prometaphase/Metaphase of the First Cleavage in Mouse Zygotes via the MAD2L1-Mediated Spindle Assembly Checkpoint.Comparison of the effects of BPA and BPAF on oocyte spindle assembly and polar body release in mice.Polo-like kinase 1 facilitates chromosome alignment during prometaphase through BubR1.Protein arginine methylation: an emerging regulator of the cell cycle.Dynein participates in chromosome segregation in fission yeast.

P2860

Q21558513-6CFAB748-814A-4A7F-9ADB-362F39705DB2 Q24303613-3B175616-A6E9-44F8-BACE-D4E4E4B503CB Q24305061-EB9B3215-FB18-43EF-8C1D-FD14F4D63CE1 Q24307413-06305275-2ED0-41EB-9A04-A902E64D3C45 Q24312788-A973FF55-4354-4B5C-A1CD-CAACB4AB5D81 Q24561583-A5CFB9AA-8CEA-4A70-9C7E-BDF240C18767 Q24670187-AA242631-39DB-450C-9291-3FCB2ACD783B Q24675117-87E76B78-9BB5-48F7-8657-44FA5750C668 Q26777317-F3EDB302-32E9-48B3-8AD2-4354C0AC85A4 Q27939198-98B0FCAA-8EC9-49A8-B01E-DFAFC951B78D Q28201606-00576125-35F5-417B-940F-898A83289264 Q28236606-BE4A0033-3E8E-4A62-9E04-C289847036A8 Q28472091-029710CC-7099-45F7-A525-75BF4DEB3F91 Q28603755-332D6437-8828-43E8-A6C3-26EA75CA9C85 Q30439536-F36F49D5-EF88-46AE-8D87-A3F9C0FAA569 Q30476121-9B5E556C-B693-482F-ABFA-514100984AA3 Q30495290-9985DC71-8D2E-41CA-96B0-1551F1680B9B Q33910498-7A4A9439-89CB-4946-9B0B-7F540F888A49 Q33926467-1B4436D7-D29A-4C01-91F4-1232A4A3CD8C Q33976673-EAB9A11A-A314-4B2E-9D22-5040A4DBD96C Q35946386-D811A8FF-D681-418B-9FF7-0586D9361CB6 Q36972632-3B1C45A4-3BA3-4341-BAF1-FCDDE09B1D11 Q36986542-4FD39C32-894D-4E95-942E-BC7531655B1F Q37174854-1408FC0A-F9F5-4630-8A42-A5FD1EBF4C36 Q37207512-91776F63-798D-4376-A690-2F29AE3B91A0 Q37271332-69F2F0E8-2D88-41E4-B2D6-5D5188DB6956 Q37638021-7FAFA810-BB83-4AF4-AEDE-B972CD3BD7CE Q37882877-46B6972A-5A9C-4839-A5FD-ACE083E9FF90 Q38219980-7C6942DA-9883-4B03-8F99-F6284DE67D8F Q40414643-56324B5B-50CA-4419-9D18-FBE161B175FE Q41499918-0B9B537F-F386-4360-B5CF-7ECBE714DB5E Q42252113-E67CE96D-848A-49E2-B898-0E0D945AB47C Q44540743-315F9809-62E7-41DC-9F31-8F8219BEC8BD Q45034296-1321CC8D-9AA9-4AAF-84E3-DBD640F9F2C7 Q47141253-602F54BE-98D0-46E5-9429-9F7CAFE7B8FC Q48579855-E0119A9A-8234-4C09-B214-FA1472E32A28 Q51991100-3603280F-91FF-400F-A5AB-B8A50B7EBBD9 Q52724818-F72A20A0-76BD-4E5A-B71C-3916E9E83D7A Q53547506-A5A76B95-2E3E-4C84-96F7-97874C1774BA

P2860

Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension.

http://www.wikidata.org/entity/Q34168724

description

2002 nî lūn-bûn

@nan

2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@ast

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@en

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@nl

type

label

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@ast

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@en

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@nl

prefLabel

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@ast

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@en

Mad2 and BubR1 function in a s ...... responds to a loss of tension.

@nl

P1433

Q34168724-54F1E195-B6BC-4D0C-A75B-DD49F4ABC18B

P1476

Q34168724-2680225F-5B6E-402C-AEBA-B91C022288D3

P2093

Q34168724-6617E2BD-E603-4522-9D46-51F39D2EC2F3

Q34168724-79E56BB1-A45B-4F14-9D0D-A4A6D3150721

P2860

Q34168724-1302FF1C-4A1A-4224-8194-36854D8A994C

Q34168724-15326BF6-EEBB-4CDD-9365-F2EC056AFF9A

Q34168724-162FF985-F5FD-4AFE-B962-6E8DA473377A

Q34168724-256A66D4-D67E-4E8D-9762-05478C7848F9

Q34168724-392F8A27-4E27-4D79-9B56-93C6E2A568CC

Q34168724-3A15C27E-41B9-40F2-9BB1-FA13B032A55C

Q34168724-3A541DBF-8647-47F3-9500-8772D80C431B

Q34168724-3D8D9B6E-10EE-4050-912F-2BFF238EE9FD

Q34168724-4C253847-5E3B-4F77-9875-6E35AE3A3B87

Q34168724-4F279059-5B44-4A22-98E0-D1A109FEF82A

P304

Q34168724-9DFF6E89-0D10-48A8-834A-717B6C887C27

P31

Q34168724-9417F5F2-B177-40C8-9FC8-67FB3A5AD1C0

P356

Q34168724-94341088-E268-43E7-95AD-4E9D4DD76D2B

P433

Q34168724-C8076BCA-BD90-4427-A66D-B6AC0FF92E1D

P478

Q34168724-A89056D6-EE27-4CD0-8FAA-3A4D7AEF1C60

P50

Q34168724-7882B9B9-EAAB-4BFF-B1CC-45C93DA96D28

P577

Q34168724-A882E3F7-9B4B-4F2D-8E51-0F26E6A0AAAE

P5875

Q34168724-954DBE4A-57DF-4252-BA59-B1DF77F66395

P698

Q34168724-F2C4D276-0080-43EB-B81D-FFD46A256BE7

P932

Q34168724-97152102-0E4D-4812-ACA3-AAEA3034A6AB

P356

MBC.E02-03-0137

P1433

Molecular Biology of the Cell

P1476

Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension

@en

P2093

E D Salmon

http://www.w3.org/2001/XMLSchema#string

Julie C Canman

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC

Identification of a human mitotic checkpoint gene: hsMAD2

The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.

Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex

Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints

MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

P304

3706-3719

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1091/MBC.E02-03-0137

http://www.w3.org/2001/XMLSchema#string

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P50

Katie B. Shannon

P577

2002-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6138028

http://www.w3.org/2001/XMLSchema#string

P698

12388768

http://www.w3.org/2001/XMLSchema#string

P932

129977

http://www.w3.org/2001/XMLSchema#string