Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.
about
IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesisRegulation of immune cell function and differentiation by the NKG2D receptorAntibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytesRegulation of Bim in Health and DiseaseAnticancer Cytokines: Biology and Clinical Effects of Interferon-α2, Interleukin (IL)-2, IL-15, IL-21, and IL-12Regulating the immune system via IL-15 transpresentationFoxo3a: an integrator of immune dysfunction during HIV infectionNKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biologyIL-15 regulates homeostasis and terminal maturation of NKT cellsInhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXAMetabolic regulator Fnip1 is crucial for iNKT lymphocyte development.Cytokines as Adjuvants for Vaccine and Cellular Therapies for Cancer.Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection.BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs.Differential mechanisms of memory CD8 T cell maintenance by individual myeloid cell types.Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity.IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis.NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human.Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes.Homeostatic proliferation generates long-lived natural killer cells that respond against viral infection.Peripheral natural killer cell maturation depends on the transcription factor AiolosIntracellular osteopontin regulates homeostasis and function of natural killer cells.The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development.Roscovitine-induced apoptosis in neutrophils and neutrophil progenitors is regulated by the Bcl-2-family members Bim, Puma, Noxa and Mcl-1Role of common-gamma chain cytokines in NK cell development and function: perspectives for immunotherapy.PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsivenessThe aged nonhematopoietic environment impairs natural killer cell maturation and function.The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM)IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα productionComplex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the γc cytokines and TGF-β1.Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia.Kruppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleenA p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion.Natural Killer Cell Memory.Pak2 Controls Acquisition of NKT Cell Fate by Regulating Expression of the Transcription Factors PLZF and Egr2.Infusion of haplo-identical killer immunoglobulin-like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation.Development and maturation of natural killer cellsThe BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland.FoxO1-mediated autophagy is required for NK cell development and innate immunity.Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155
P2860
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P2860
Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@ast
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@en
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@nl
type
label
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@ast
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@en
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@nl
prefLabel
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@ast
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@en
Interleukin 15-mediated surviv ...... ons among Bim, Noxa and Mcl-1.
@nl
P2093
P2860
P50
P356
P1433
P1476
Interleukin 15-mediated surviv ...... ions among Bim, Noxa and Mcl-1
@en
P2093
Edwina Naik
Grant Dewson
Hyacinth Tabarias
Mariapia A Degli-Esposti
Nicholas D Huntington
Noboru Motoyama
Priscilla Gunn
Simon N Willis
P2860
P304
P356
10.1038/NI1487
P407
P50
P577
2007-07-08T00:00:00Z