Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
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The evolution of genome-scale models of cancer metabolismThe mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenaseStable isotope-resolved metabolomics and applications for drug developmentMitochondrial metabolic remodeling in response to genetic and environmental perturbationsTranscriptomics resources of human tissues andĀ organsMathematical models of cancer metabolismHypoxia and metabolic adaptation of cancer cellsAminolevulinic Acid-Based Tumor Detection and Therapy: Molecular Mechanisms and Strategies for EnhancementComputational approaches for understanding energy metabolismIDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in gliomaGenetically-defined metabolic reprogramming in cancerMetabolomics in the studies of islet autoimmunity and type 1 diabetesPI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.Oncometabolites: Unconventional triggers of oncogenic signalling cascadesReduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathwayReconstruction of Tissue-Specific Metabolic Networks Using CORDAThe Keap1-Nrf2 system in cancers: stress response and anabolic metabolismAssessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (DIGE)Inferring metabolic states in uncharacterized environments using gene-expression measurementsGlucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cellsMetabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinomaAssessment of FBA Based Gene Essentiality Analysis in Cancer with a Fast Context-Specific Network Reconstruction MethodRecon 2.2: from reconstruction to model of human metabolismA community-driven global reconstruction of human metabolism.Mitochondria and cancerMechanistic systems modeling to guide drug discovery and developmentReconciling a Salmonella enterica metabolic model with experimental data confirms that overexpression of the glyoxylate shunt can rescue a lethal ppc deletion mutantPyruvate carboxylase is critical for non-small-cell lung cancer proliferation.ResponseNet2.0: Revealing signaling and regulatory pathways connecting your proteins and genes--now with human data.Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathwaysReconstruction of genome-scale human metabolic models using omics data.Prediction of intracellular metabolic states from extracellular metabolomic dataA Method to Constrain Genome-Scale Models with 13C Labeling Data.Integrative analysis of human omics data using biomolecular networks.Analysing Algorithms and Data Sources for the Tissue-Specific Reconstruction of Liver Healthy and Cancer Cells.Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling.Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks.Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism.
P2860
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P2860
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
description
2011 nĆ® lÅ«n-bĆ»n
@nan
2011 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕ£ÕøÕ½ÕæÕøÕ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
2011 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Ö
Õ£ÕøÕ½ÕæÕøÕ½Õ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2011幓ć®č«ę
@ja
2011幓č«ę
@yue
2011幓č«ę
@zh-hant
2011幓č«ę
@zh-hk
2011幓č«ę
@zh-mo
2011幓č«ę
@zh-tw
2011幓č®ŗę
@wuu
name
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@ast
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@en
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@nl
type
label
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@ast
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@en
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@nl
prefLabel
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@ast
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@en
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@nl
P2093
P2860
P4510
P50
P356
P1433
P1476
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
@en
P2093
Ann Hedley
Barbara Chaneton
Dave G Watson
Elaine D MacKenzie
Gabriela Kalna
Ian P M Tomlinson
Kartik N Rajagopalan
Liang Zheng
Livnat Jerby
Massimo Micaroni
P2860
P2888
P304
P356
10.1038/NATURE10363
P407
P577
2011-08-17T00:00:00Z
P5875
P6179
1044931865