T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse.
about
Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophagesPI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization.High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestryDef-6, a guanine nucleotide exchange factor for Rac1, interacts with the skeletal muscle integrin chain alpha7A and influences myoblast differentiationDown regulation of genes involved in T cell polarity and motility during the induction of heart allograft tolerance by allochimeric MHC I.SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cellsSLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis.Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regionsIRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Def6 is required for convergent extension movements during zebrafish gastrulation downstream of Wnt5b signaling.Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunityCooperation of DEF6 with activated Rac in regulating cell morphology.Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells.IRF-4 suppresses BCR/ABL transformation of myeloid cells in a DNA binding-independent manner.Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity.DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies.Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells.SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.SLAT regulates CD8+ T cell clonal expansion in a Cdc42- and NFAT1-dependent mannerRho family GTPases and their regulators in lymphocytes.IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor.Regulation of TLR4-mediated signaling by IBP/Def6, a novel activator of Rho GTPases.BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.Stimulatory and suppressive signal transduction regulates vasoactive intestinal peptide receptor-1 (VPAC-1) in primary mouse CD4 T cells.SLAT negatively regulates RANKL-induced osteoclast differentiation.Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.The F-actin modulator SWAP-70 controls podosome patterning in osteoclasts.Ectopically expressed IBP promotes cell proliferation in oral squamous cell carcinoma.Dendritic cell podosome dynamics does not depend on the F-actin regulator SWAP-70.Identification of a Novel Alternatively Spliced Form of Inflammatory Regulator SWAP-70-Like Adapter of T Cells.Role of guanine nucleotide exchange factor-H1 in complement-mediated RhoA activation in glomerular epithelial cells.SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells.Structure analysis between the SWAP-70 RHO-GEF and the newly described PLD2-GEFDef-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι.Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.Regulation of Effector Treg Cells in Murine Lupus.Fine tuning of IRF-4 expression by SWAP-70 controls the initiation of plasma cell development.
P2860
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P2860
T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
T cell receptor engagement lea ...... to the immunological synapse.
@ast
T cell receptor engagement lea ...... to the immunological synapse.
@en
T cell receptor engagement lea ...... to the immunological synapse.
@nl
type
label
T cell receptor engagement lea ...... to the immunological synapse.
@ast
T cell receptor engagement lea ...... to the immunological synapse.
@en
T cell receptor engagement lea ...... to the immunological synapse.
@nl
prefLabel
T cell receptor engagement lea ...... to the immunological synapse.
@ast
T cell receptor engagement lea ...... to the immunological synapse.
@en
T cell receptor engagement lea ...... to the immunological synapse.
@nl
P2093
P2860
P356
P1476
T cell receptor engagement lea ...... to the immunological synapse.
@en
P2093
Alessandra B Pernis
Andrea E Lee
Chuanmin Hu
Dianne Cox
Jessica C Fanzo
Sanjay Gupta
So Young Jang
Steven Greenberg
P2860
P304
43541-43549
P356
10.1074/JBC.M308960200
P407
P577
2003-08-15T00:00:00Z