Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?
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Oncolytic Replication of E1b-Deleted AdenovirusesAdenoviral vectors for prodrug activation-based gene therapy for cancerMolecular basis for viral selective replication in cancer cells: activation of CDK2 by adenovirus-induced cyclin EAdenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblastsConstruction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemiasStrategies for reversing drug resistance.Gene therapy progress and prospects: cancer gene therapy using tumour suppressor genes.Tissue-specific promoters for cancer gene therapy.Oncolytic adenovirus targeting cyclin E overexpression repressed tumor growth in syngeneic immunocompetent mice.Oncolytic viruses for cancer therapy II. Cell-internal factors for conditional growth in neoplastic cells.Complete eradication of xenograft hepatoma by oncolytic adenovirus ZD55 harboring TRAIL-IETD-Smac gene with broad antitumor effectInactivating intracellular antiviral responses during adenovirus infection.[The use of p53 as a tool for human cancer therapy].Potent antitumor activity of oncolytic adenovirus expressing Beclin-1 via induction of autophagic cell death in leukemiaHuman telomerase reverse transcriptase promoter-driven oncolytic adenovirus with E1B-19 kDa and E1B-55 kDa gene deletionsAdenoviral vector-based strategies for cancer therapy.Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.Enhanced antitumor activity by a selective conditionally replicating adenovirus combining with MDA-7/interleukin-24 for B-lymphoblastic leukemia via induction of apoptosis.Selective replication of E1B55K-deleted adenoviruses depends on enhanced E1A expression in cancer cells.E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection.Radiation increases the activity of oncolytic adenovirus cancer gene therapy vectors that overexpress the ADP (E3-11.6K) protein.Cancer therapy utilizing an adenoviral vector expressing only E1A.Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy.Sodium iodide symporter SPECT imaging of a patient treated with oncolytic adenovirus Ad5/3-Δ24-hNISA novel tetracycline-controlled transactivator-transrepressor system enables external control of oncolytic adenovirus replication.Achilles' heel of cancer?
P2860
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P2860
Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Does the antitumor adenovirus ...... defective in the p53 pathway?
@ast
Does the antitumor adenovirus ...... defective in the p53 pathway?
@en
Does the antitumor adenovirus ...... defective in the p53 pathway?
@nl
type
label
Does the antitumor adenovirus ...... defective in the p53 pathway?
@ast
Does the antitumor adenovirus ...... defective in the p53 pathway?
@en
Does the antitumor adenovirus ...... defective in the p53 pathway?
@nl
prefLabel
Does the antitumor adenovirus ...... defective in the p53 pathway?
@ast
Does the antitumor adenovirus ...... defective in the p53 pathway?
@en
Does the antitumor adenovirus ...... defective in the p53 pathway?
@nl
P2860
P1433
P1476
Does the antitumor adenovirus ...... defective in the p53 pathway?
@en
P2093
A W Braithwaite
P2860
P304
P356
10.1128/JVI.75.12.5443-5447.2001
P407
P577
2001-06-01T00:00:00Z