E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection.
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Oncolytic Replication of E1b-Deleted AdenovirusesMolecular basis for viral selective replication in cancer cells: activation of CDK2 by adenovirus-induced cyclin EAdenovirus type 5 early region 1B 55-kDa oncoprotein can promote cell transformation by a mechanism independent from blocking p53-activated transcriptionCombining Oncolytic Virotherapy with p53 Tumor Suppressor Gene TherapyTargeting of p53-transcriptional dysfunction by conditionally replicating adenovirus is not limited by p53-homologues.The human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells.p400 is required for E1A to promote apoptosis.Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus.The repression domain of the E1B 55-kilodalton protein participates in countering interferon-induced inhibition of adenovirus replication.Impact of the adenoviral E4 Orf3 protein on the activity and posttranslational modification of p53.Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agentsTimely synthesis of the adenovirus type 5 E1B 55-kilodalton protein is required for efficient genome replication in normal human cells.Viruses - seeking and destroying the tumor program.Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.Long story short: p53 mediates innate immunity.The adenoviral E1B 55-kilodalton protein controls expression of immune response genes but not p53-dependent transcription.alpha-Tocopheryl succinate and derivatives mediate the transcriptional repression of androgen receptor in prostate cancer cells by targeting the PP2A-JNK-Sp1-signaling axis.Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation.Extensive post-translational modification of active and inactivated forms of endogenous p53.The human adenovirus 5 L4 promoter is activated by cellular stress response protein p53.Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex.Infection with E1B-mutant adenovirus stabilizes p53 but blocks p53 acetylation and activity through E1A.Adenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication.Modification of the p53 transgene of a replication-competent adenovirus prevents mdm2- and E1b-55kD-mediated degradation of p53.Selective replication of E1B55K-deleted adenoviruses depends on enhanced E1A expression in cancer cells.Normal human cell proteins that interact with the adenovirus type 5 E1B 55kDa protein.Mitochondrial localization of p53 during adenovirus infection and regulation of its activity by E1B-19K.Tumor-specific cytolysis caused by an E1B55K-attenuated adenovirus in nasopharyngeal carcinoma is augmented by cisplatin.
P2860
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P2860
E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
E1B-55-kilodalton protein is n ...... n during adenovirus infection.
@en
type
label
E1B-55-kilodalton protein is n ...... n during adenovirus infection.
@en
prefLabel
E1B-55-kilodalton protein is n ...... n during adenovirus infection.
@en
P2860
P1433
P1476
E1B-55-kilodalton protein is n ...... n during adenovirus infection.
@en
P2093
P2860
P304
P356
10.1128/JVI.78.14.7685-7697.2004
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P577
2004-07-01T00:00:00Z