Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis.
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Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression.Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cellsCD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signalsGlobal analysis of the eukaryotic pathways and networks regulated by Salmonella typhimurium in mouse intestinal infection in vivo.The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammationDynamic modularity of host protein interaction networks in Salmonella Typhi infection.IL-4 acts as a potent stimulator of IFN-γ expression in CD8+ T cells through STAT6-dependent and independent induction of Eomesodermin and T-bet.The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes.Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury.Insulin receptor substrate-2 maintains predominance of anabolic function over catabolic function of osteoblasts.Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation.CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages.Macrophage peroxisome proliferator activated receptor gamma as a therapeutic target to combat Type 2 diabetes.Interleukin-4, interleukin-13, signal transducer and activator of transcription factor 6, and allergic asthma.Impact of Enriched Environment on Murine T Cell Differentiation and Gene Expression ProfileCombinatorial Signal Transduction Responses Mediated by Interleukin-2 and -4 Receptors in a Helper TH2 Cell Line.Psychoneuroimmune implications of type 2 diabetes: reduxType I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages.Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.Enhanced apoptosis of peripheral CD5-negative B lymphocytes from chronically hepatitis C virus-infected patients: reversal after antiviral treatment.The potential for genetically altered microglia to influence glioma treatment.Suppressor of cytokine signaling 3 regulates proliferation and activation of T-helper cells.IL-4: an important cytokine in determining the fate of T cells.Human and rodent pancreatic beta-cells express IL-4 receptors and IL-4 protects against beta-cell apoptosis by activation of the PI3K and JAK/STAT pathways.Increased levels of Gab1 and Gab2 adaptor proteins skew interleukin-4 (IL-4) signaling toward M2 macrophage-driven pulmonary fibrosis in mice.Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.Basophils inhibit proliferation of CD4⁺ T cells in autologous and allogeneic mixed lymphocyte reactions and limit disease activity in a murine model of graft versus host disease.The TSC-mTOR pathway regulates macrophage polarization.The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling.IL-4 independent nuclear translocalization of STAT6 in HeLa cells by entry of Toxoplasma gondii.Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL.Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells.c-Maf increases apoptosis in peripheral CD8 cells by transactivating Caspase 6.High expression of IL-4R enhances proliferation and invasion of hepatocellular carcinoma cells.IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View.
P2860
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P2860
Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Stat6 and IRS-2 cooperate in i ...... pendent rescue from apoptosis.
@ast
Stat6 and IRS-2 cooperate in i ...... pendent rescue from apoptosis.
@en
Stat6 and IRS-2 cooperate in interleukin 4
@nl
type
label
Stat6 and IRS-2 cooperate in i ...... pendent rescue from apoptosis.
@ast
Stat6 and IRS-2 cooperate in i ...... pendent rescue from apoptosis.
@en
Stat6 and IRS-2 cooperate in interleukin 4
@nl
prefLabel
Stat6 and IRS-2 cooperate in i ...... pendent rescue from apoptosis.
@ast
Stat6 and IRS-2 cooperate in i ...... pendent rescue from apoptosis.
@en
Stat6 and IRS-2 cooperate in interleukin 4
@nl
P2093
P2860
P1476
Stat6 and IRS-2 cooperate in i ...... pendent rescue from apoptosis.
@en
P2093
Andrea L Wurster
Michael J Grusby
Morris F White
Tohru Uchida
P2860
P304
P356
10.1128/MCB.22.1.117-126.2002
P407
P577
2002-01-01T00:00:00Z