Pluripotent hematopoietic stem cells contain high levels of mRNA for c-kit, GATA-2, p45 NF-E2, and c-myb and low levels or no mRNA for c-fms and the receptors for granulocyte colony-stimulating factor and interleukins 5 and 7.
about
Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoproteinX-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interactionSON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 clusterNF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitroCbfb/Runx1 repression-independent blockage of differentiation and accumulation of Csf2rb-expressing cells by Cbfb-MYH11.The role of GATA2 in lethal prostate cancer aggressiveness.GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion.Pluripotent hemopoietic stem cells are c-kit<low.Rearrangements of chromosome band 3q21 in myeloid leukemia.Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation.GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodelingA novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2.c-Myb Binding Sites in Haematopoietic Chromatin LandscapesCoregulator-dependent facilitation of chromatin occupancy by GATA-1.Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34 protein in primary human hematopoietic progenitors from bone marrow.A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activityGATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia.Genetic induction of immune tolerance to human clotting factor VIII in a mouse model for hemophilia AGATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cellsMyb proteins: angels and demons in normal and transformed cells.Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cellsFunctional and molecular characterization of mouse Gata2-independent hematopoietic progenitorsMutations in GATA2 cause human NK cell deficiency with specific loss of the CD56(bright) subset.Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene.The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction.Gata2 is required for HSC generation and survival.The biochemistry of hematopoietic stem cell development.GATA-1-mediated transcriptional repression yields persistent transcription factor IIB-chromatin complexes.Dynamic GATA factor interplay at a multicomponent regulatory region of the GATA-2 locus.Distinct functions of dispersed GATA factor complexes at an endogenous gene locus.Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hematopoietic and endothelial cells.PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors.GATA transcription factors inhibit cytokine-dependent growth and survival of a hematopoietic cell line through the inhibition of STAT3 activity.VLA-4 mediated adhesion to bone marrow stromal cells confers chemoresistance to adherent lymphoma cells.Alternative promoters regulate transcription of the mouse GATA-2 gene.Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase.The epigenetic modifiers 5-aza-2'-deoxycytidine and trichostatin A influence adipocyte differentiation in human mesenchymal stem cells.Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysisContext-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation.
P2860
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P2860
Pluripotent hematopoietic stem cells contain high levels of mRNA for c-kit, GATA-2, p45 NF-E2, and c-myb and low levels or no mRNA for c-fms and the receptors for granulocyte colony-stimulating factor and interleukins 5 and 7.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@ast
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@en
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@nl
type
label
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@ast
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@en
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@nl
prefLabel
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@ast
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@en
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@nl
P2093
P2860
P356
P1476
Pluripotent hematopoietic stem ...... ctor and interleukins 5 and 7.
@en
P2093
Anderson S
Biesecker LG
Sorrentino BP
P2860
P304
P356
10.1073/PNAS.92.10.4601
P407
P577
1995-05-01T00:00:00Z