Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential.
about
Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesisNon-transcriptional interactions of Hox proteins: inventory, facts, and future directionsThe cell cycle and pluripotencyStructural basis for homeodomain recognition by the cell-cycle regulator Geminin(1)H, (15)N and (13)C chemical shift assignments of the homeodomain of Hoxc9 in complex with the cell cycle regulator Geminin.Hoxa9 transduction induces hematopoietic stem and progenitor cell activity through direct down-regulation of geminin proteinMolecular Analysis of the HOXA2-Dependent Degradation of RCHY1.Manipulation of Cell Cycle and Chromatin Configuration by Means of Cell-Penetrating GemininScmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4Dominant-negative STAT1 SH2 domain mutations in unrelated patients with Mendelian susceptibility to mycobacterial diseaseTranscription of the Geminin gene is regulated by a negative-feedback loop.Role of Geminin in cell fate determination of hematopoietic stem cells (HSCs).The homeodomain transcription factor Hoxa2 interacts with and promotes the proteasomal degradation of the E3 ubiquitin protein ligase RCHY1.Ectopic expression of Hoxb4a in hemangioblasts promotes hematopoietic development in early embryogenesis of zebrafish.
P2860
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P2860
Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
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name
Hoxb4 transduction down-regula ...... with proliferation potential.
@ast
Hoxb4 transduction down-regula ...... with proliferation potential.
@en
Hoxb4 transduction down-regula ...... with proliferation potential.
@nl
type
label
Hoxb4 transduction down-regula ...... with proliferation potential.
@ast
Hoxb4 transduction down-regula ...... with proliferation potential.
@en
Hoxb4 transduction down-regula ...... with proliferation potential.
@nl
prefLabel
Hoxb4 transduction down-regula ...... with proliferation potential.
@ast
Hoxb4 transduction down-regula ...... with proliferation potential.
@en
Hoxb4 transduction down-regula ...... with proliferation potential.
@nl
P2093
P2860
P356
P1476
Hoxb4 transduction down-regula ...... with proliferation potential.
@en
P2093
Kiyoshi Ohtani
Masao Kobayashi
Miyuki Tsumura
Motoaki Ohtsubo
Sayaka Mori
Shin'ichiro Yasunaga
Tomohiko Ohta
Yoshihiro Takihara
Yoshinori Ohno
P2860
P304
21529-21534
P356
10.1073/PNAS.1011054107
P407
P577
2010-11-22T00:00:00Z