Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function.
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GABA A receptors: subtypes provide diversity of function and pharmacologyInternational Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. UpdateDevelopmental modulation of GABA(A) receptor function by RNA editingIonotropic GABA receptor antagonism-induced adverse outcome pathways for potential neurotoxicity biomarkersStructure, function, and modulation of GABA(A) receptorsMapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogueAn Electrostatic Funnel in the GABA-Binding PathwayPhoto-antagonism of the GABAA receptor.Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA) receptors.Expression of GABAergic receptors in mouse taste receptor cellsNew insights into the GABA(A) receptor structure and orthosteric ligand binding: receptor modeling guided by experimental data.Molecular targets and mechanisms for ethanol action in glycine receptorsEditing of neurotransmitter receptor and ion channel RNAs in the nervous systemLinking of Glycine Receptor Transmembrane Segments Three and Four Allows Assignment of Intrasubunit-Facing Residues.Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation.The major central endocannabinoid directly acts at GABA(A) receptors.Structural answers and persistent questions about how nicotinic receptors work.Anesthetic sites and allosteric mechanisms of action on Cys-loop ligand-gated ion channels.Structural basis for alcohol modulation of a pentameric ligand-gated ion channelThe GABAA receptor alpha+beta- interface: a novel target for subtype selective drugsThe dynamic modulation of GABA(A) receptor trafficking and its role in regulating the plasticity of inhibitory synapses.Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetateCross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activationEstimating the efficiency of benzodiazepines on GABA(A) receptors comprising gamma1 or gamma2 subunits.Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interfaceInter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor.GABA-induced intersubunit conformational movement in the GABAA receptor alpha 1M1-beta 2M3 transmembrane subunit interface: experimental basis for homology modeling of an intravenous anesthetic binding site.Inhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sitesAssessment of homology templates and an anesthetic binding site within the γ-aminobutyric acid receptor.Modeling neuronal nicotinic and GABA receptors: important interface salt-links and protein dynamics.Unexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ β- Site.Structural models of ligand-gated ion channels: sites of action for anesthetics and ethanol.New insights into the molecular mechanisms of general anaesthetics.A novel GABA(A) receptor pharmacology: drugs interacting with the α(+) β(-) interface.Pharmacophore models for GABA(A) modulators: implications in CNS drug discovery.Benzodiazepine receptor ligands: a patent review (2006-2012).Probing the orthosteric binding site of GABAA receptors with heterocyclic GABA carboxylic acid bioisosteres.Γ-aminobutyric acid receptors affect the progression and migration of tumor cells.Orthosteric- versus allosteric-dependent activation of the GABAA receptor requires numerically distinct subunit level rearrangements.
P2860
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P2860
Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Comparative models of GABAA re ...... in pharmacology and function.
@ast
Comparative models of GABAA re ...... in pharmacology and function.
@en
Comparative models of GABAA re ...... in pharmacology and function.
@nl
type
label
Comparative models of GABAA re ...... in pharmacology and function.
@ast
Comparative models of GABAA re ...... in pharmacology and function.
@en
Comparative models of GABAA re ...... in pharmacology and function.
@nl
prefLabel
Comparative models of GABAA re ...... in pharmacology and function.
@ast
Comparative models of GABAA re ...... in pharmacology and function.
@en
Comparative models of GABAA re ...... in pharmacology and function.
@nl
P50
P356
P1476
Comparative models of GABAA re ...... s in pharmacology and function
@en
P2093
Stefan Bruckner
P304
P356
10.1124/MOL.105.015982
P577
2005-08-15T00:00:00Z