Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system.
about
Proapoptotic function of the retinoblastoma tumor suppressor proteinEssential role of retinoblastoma protein in mammalian hair cell development and hearing.miR-17~92 cooperates with RB pathway mutations to promote retinoblastomaTranscriptional control of stem cell fate by E2Fs and pocket proteinsGenetic interaction between Rb and K-ras in the control of differentiation and tumor suppressionThe retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.Regulation of neuron survival and death by p130 and associated chromatin modifiers.A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration.Elevated Id2 expression results in precocious neural stem cell depletion and abnormal brain development.Mouse models of human familial cancer syndromes.Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.Enhanced proliferation of monolayer cultures of embryonic stem (ES) cell-derived cardiomyocytes following acute loss of retinoblastoma.The retinoblastoma tumor-suppressor gene, the exception that proves the ruleE2F4 cooperates with pRB in the development of extra-embryonic tissues.Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.Coupling of caspase-9 to Apaf1 in response to loss of pRb or cytotoxic drugs is cell-type-specific.G1 arrest and differentiation can occur independently of Rb family function.Cell cycle molecules define a pathway required for neuron death in development and disease.XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice.Rb is dispensable for self-renewal and multilineage differentiation of adult hematopoietic stem cellsCooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain.Visualizing dynamic E2F-mediated repression in vivo.Coordinated regulation of life and death by RB.Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb-deficient mice.Lineage-specific regulation of epigenetic modifier genes in human liver and brainCell cycle molecules and vertebrate neuron death: E2F at the hub.Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplificationGenetic evidence for functional dependency of p18Ink4c on Cdk4.lin-35/Rb and the CoREST ortholog spr-1 coordinately regulate vulval morphogenesis and gonad development in C. elegansUnique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functionsHypoxic stress underlies defects in erythroblast islands in the Rb-null mouse.The search for the retinoblastoma cell of origin.Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells.The RB protein family in retinal development and retinoblastoma: new insights from new mouse models.The retinoblastoma tumor suppressor and stem cell biology.p107 regulates neural precursor cells in the mammalian brainPocket protein function in melanocyte homeostasis and neoplasia.Cell type-specific effects of Rb deletion in the murine retina.Dp1 is largely dispensable for embryonic development.Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease
P2860
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P2860
Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Conditional mutation of Rb cau ...... in the central nervous system.
@ast
Conditional mutation of Rb cau ...... in the central nervous system.
@en
Conditional mutation of Rb cau ...... in the central nervous system.
@nl
type
label
Conditional mutation of Rb cau ...... in the central nervous system.
@ast
Conditional mutation of Rb cau ...... in the central nervous system.
@en
Conditional mutation of Rb cau ...... in the central nervous system.
@nl
prefLabel
Conditional mutation of Rb cau ...... in the central nervous system.
@ast
Conditional mutation of Rb cau ...... in the central nervous system.
@en
Conditional mutation of Rb cau ...... in the central nervous system.
@nl
P2093
P2860
P1476
Conditional mutation of Rb cau ...... in the central nervous system.
@en
P2093
P2860
P304
P356
10.1128/MCB.23.3.1044-1053.2003
P407
P577
2003-02-01T00:00:00Z