The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion - Wikidata - awgldk - TriplyDB

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

http://www.wikidata.org/entity/Q34468460

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The epigenetic landscape of acute myeloid leukemia Polycomb group genes: keeping stem cell activity in balance The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells Epigenetic perturbations in aging stem cells Regulation of T Cell Differentiation and Function by EZH2 When stem cells grow old: phenotypes and mechanisms of stem cell aging EZH2 in normal hematopoiesis and hematological malignancies Recent progress toward epigenetic therapies: the example of mixed lineage leukemia The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes Increased expression of PcG protein YY1 negatively regulates B cell development while allowing accumulation of myeloid cells and LT-HSC cells Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2.Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation Alterations in chromatin are associated with increases in collagen III expression in aging nephropathy Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions Polycomb silencers control cell fate, development and cancer Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic stem cells Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells.Large scale gene expression profiles of regenerating inner ear sensory epithelia.Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles Cdc42 and aging of hematopoietic stem cells.Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis.p53-mediated hematopoietic stem and progenitor cell competition.Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging.EZH2 depletion blocks the proliferation of colon cancer cells.Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.Identification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host disease The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation.Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer.Bmi1 confers resistance to oxidative stress on hematopoietic stem cells TAP-deficient human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells.Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes EZH2 in normal and malignant hematopoiesis.The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.Epigenetic control of hematopoietic stem cell aging the case of Ezh2.

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The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

http://www.wikidata.org/entity/Q34468460

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

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2005年論文

@zh-tw

2005年论文

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name

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@ast

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@en

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@nl

type

label

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@ast

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@en

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@nl

prefLabel

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@ast

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@en

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

@nl

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The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

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Aletta de Boer

http://www.w3.org/2001/XMLSchema#string

Bert Dontje

http://www.w3.org/2001/XMLSchema#string

Ellen Weersing

http://www.w3.org/2001/XMLSchema#string

Gerald de Haan

http://www.w3.org/2001/XMLSchema#string

José Douma

http://www.w3.org/2001/XMLSchema#string

Leonid V Bystrykh

http://www.w3.org/2001/XMLSchema#string

Leonie M Kamminga

http://www.w3.org/2001/XMLSchema#string

Sita Houwer

http://www.w3.org/2001/XMLSchema#string

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Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes.

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Expression and function of c-kit in hemopoietic progenitor cells

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

The language of covalent histone modifications

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

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2170-2179

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5

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1895717

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