Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health.
about
Analyzing the roles of multi-functional proteins in cells: The case of arrestins and GRKsPhotoreceptor signaling: supporting vision across a wide range of light intensities.Variation in Rhodopsin Kinase Expression Alters the Dim Flash Response Shut Off and the Light Adaptation in Rod PhotoreceptorsIdentification of receptor binding-induced conformational changes in non-visual arrestins.Progressive reduction of its expression in rods reveals two pools of arrestin-1 in the outer segment with different roles in photoresponse recovery.The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activationHybrid mice reveal parent-of-origin and Cis- and trans-regulatory effects in the retinaRobust self-association is a common feature of mammalian visual arrestin-1.Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo.Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins.The functional cycle of visual arrestins in photoreceptor cells.Manipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestinsConformation of receptor-bound visual arrestin.Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsinEngineering visual arrestin-1 with special functional characteristicsCritical role of the central 139-loop in stability and binding selectivity of arrestin-1.Visual arrestin interaction with clathrin adaptor AP-2 regulates photoreceptor survival in the vertebrate retina.Rhodopsin kinase and arrestin binding control the decay of photoactivated rhodopsin and dark adaptation of mouse rods.Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods.Protein sorting, targeting and trafficking in photoreceptor cellsConstitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 bindingJNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinasesArrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding.Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1.Separation of photoreceptor cell compartments in mouse retina for protein analysis.Synthetic biology with surgical precision: targeted reengineering of signaling proteins.Structural determinants of arrestin functionsBeyond traditional pharmacology: new tools and approaches.Arrestins: Critical Players in Trafficking of Many GPCRs.Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypesPhosphorylation-independent suppression of light-activated visual pigment by arrestin in carp rods and cones.Arrestin-3-Dependent Activation of c-Jun N-Terminal Kinases (JNKs).Self-association of arrestin family members.Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant.Arrestins in apoptosis.Ubiquitin ligase parkin promotes Mdm2-arrestin interaction but inhibits arrestin ubiquitinationEnhanced phosphorylation-independent arrestins and gene therapy.Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors.Arrestin expression in E. coli and purification.Exploring the rate-limiting steps in visual phototransduction recovery by bottom-up kinetic modeling.
P2860
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P2860
Arrestin-1 expression level in rods: balancing functional performance and photoreceptor health.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Arrestin-1 expression level in ...... ance and photoreceptor health.
@ast
Arrestin-1 expression level in ...... ance and photoreceptor health.
@en
Arrestin-1 expression level in ...... ance and photoreceptor health.
@nl
type
label
Arrestin-1 expression level in ...... ance and photoreceptor health.
@ast
Arrestin-1 expression level in ...... ance and photoreceptor health.
@en
Arrestin-1 expression level in ...... ance and photoreceptor health.
@nl
prefLabel
Arrestin-1 expression level in ...... ance and photoreceptor health.
@ast
Arrestin-1 expression level in ...... ance and photoreceptor health.
@en
Arrestin-1 expression level in ...... ance and photoreceptor health.
@nl
P2093
P2860
P1433
P1476
Arrestin-1 expression level in ...... ance and photoreceptor health.
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P2093
P2860
P356
10.1016/J.NEUROSCIENCE.2010.11.009
P407
P577
2010-11-12T00:00:00Z