Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma - Wikidata - awgldk - TriplyDB

Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma

Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma

http://www.wikidata.org/entity/Q34515560

about

LKB1 exonic and whole gene deletions are a common cause of Peutz-Jeghers syndrome Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366 LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.Genetic testing for hereditary colorectal cancer.Lower gastrointestinal tract cancer predisposition syndromes Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.LKB1, a protein kinase regulating cell proliferation and polarity.Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.Genotype-phenotype correlations in Peutz-Jeghers syndrome LKB1, the multitasking tumour suppressor kinase Identification of patients at risk for hereditary colorectal cancer High Resolution Melting analysis as a rapid and efficient method of screening for small mutations in the STK11 gene in patients with Peutz-Jeghers syndrome.Endopancreatic bile duct cholangiocarcinoma in a patient with peutz-jeghers syndrome.Cancer risks in LKB1 germline mutation carriers.Clinical characteristics and STK11 gene mutations in Chinese children with Peutz-Jeghers syndrome The hamartomatous polyposis syndromes: a clinical and molecular review.Three novel mutations of STK11 gene in Chinese patients with Peutz-Jeghers syndrome.Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates.LKB1; linking cell structure and tumor suppression.Peutz-Jeghers syndrome: diagnostic and therapeutic approach.The LKB1 complex-AMPK pathway: the tree that hides the forest STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome.Identification of a novel de novo STK11 mutation in a Chinese child with Peutz-Jeghers syndrome.LKB1 gene mutations in Japanese lung cancer patients.Peutz-Jeghers syndrome: early clinical expression of a new STK11 gene variant.Complete germline deletion of the STK11 gene in a family with Peutz-Jeghers syndrome.

P2860

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P2860

Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma

http://www.wikidata.org/entity/Q34515560

description

2001 nî lūn-bûn

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2001 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2001 թվականի հունիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

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Journal of Medical Genetics

P1476

Peutz-Jeghers families unlinke ...... imitive biliary adenocarcinoma

@en

P2093

Boisson C

http://www.w3.org/2001/XMLSchema#string

Olschwang S

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Thomas G

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P2860

Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity

Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer

The molecular basis and clinical aspects of Peutz-Jeghers syndrome.

Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3.

Germline mutations of the LKB1 (STK11) gene in Peutz-Jeghers patients.

PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome.

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356-360

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scholarly article

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10.1136/JMG.38.6.356

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6

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38

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11389158

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1734902

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