Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway. - Wikidata - awgldk - TriplyDB

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

http://www.wikidata.org/entity/Q34534129

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Role of EPAC in cAMP-Mediated Actions in Adrenocortical Cells Bridging cell surface receptor with nuclear receptors in control of bile acid homeostasis LKB1/AMPK and PKA control ABCB11 trafficking and polarization in hepatocytes Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytes Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs.Biotunable acoustic node assembly of organoids.AMPK Activation Prevents and Reverses Drug-Induced Mitochondrial and Hepatocyte Injury by Promoting Mitochondrial Fusion and Function The number of metabolic abnormalities associated with the risk of gallstones in a non-diabetic population.Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation.Bile formation and secretion.Transport in technicolor: mapping ATP-binding cassette transporters in sea urchin embryos.DNA methylation of alternative promoters directs tissue specific expression of Epac2 isoforms Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.Cellular mechanism of bile acid-accelerated hepatocyte polarity.Structural and functional hepatocyte polarity and liver disease.Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.Deoxypodophyllotoxin suppresses tumor vasculature in HUVECs by promoting cytoskeleton remodeling through LKB1-AMPK dependent Rho A activatio.Protection against cardiac hypertrophy by geniposide involves the GLP-1 receptor / AMPKα signalling pathway Coordinated elevation of mitochondrial oxidative phosphorylation and autophagy help drive hepatocyte polarization.Hepatocyte polarity Autocrine regulation of biliary pathology by activated cholangiocytes.Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo Role of LKB1-SAD/MARK pathway in neuronal polarization.Epithelial cell polarity, stem cells and cancer.Adenylyl cyclases in the digestive system.The unique polarity phenotype of hepatocytes.Sry HMG box protein 9-positive (Sox9+) epithelial cell adhesion molecule-negative (EpCAM-) biphenotypic cells derived from hepatocytes are involved in mouse liver regeneration.Morphogenesis of liver epithelial cells.PKA/AMPK signaling in relation to adiponectin's antiproliferative effect on multiple myeloma cells.Effect of dietary nonstructural carbohydrate content on activation of 5'-adenosine monophosphate-activated protein kinase in liver, skeletal muscle, and digital laminae of lean and obese ponies.CTRP3 attenuates cardiac dysfunction, inflammation, oxidative stress and cell death in diabetic cardiomyopathy in rats.Biliary fibrosis drives liver repopulation and phenotype transition of transplanted hepatocytes Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling.Build them up and break them down: Tight junctions of cell lines expressing typical hepatocyte polarity with a varied repertoire of claudins.Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats.Mechanical compaction directly modulates the dynamics of bile canaliculi formation.Growth and development of a new subspecialty: pediatric hepatology.Liver serine palmitoyltransferase activity deficiency in early life impairs adherens junctions and promotes tumorigenesis.Extracellular matrix scaffolding guides lumen elongation by inducing anisotropic intercellular mechanical tension.

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P2860

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

http://www.wikidata.org/entity/Q34534129

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

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name

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@ast

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@en

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@nl

type

label

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@ast

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@en

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@nl

prefLabel

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@ast

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@en

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

@en

P2093

Dong Fu

http://www.w3.org/2001/XMLSchema#string

Irwin M Arias

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Yoshiyuki Wakabayashi

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P2860

New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion

Rab11a and myosin Vb are required for bile canalicular formation in WIF-B9 cells

Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth

Bile acids stimulate PKCalpha autophosphorylation and activation: role in the attenuation of prostaglandin E1-induced cAMP production in human dermal fibroblasts

The MAPK signaling cascade

Uncoupling of the LKB1-AMPKalpha energy sensor pathway by growth factors and oncogenic BRAF

Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.

Signal transduction and hepatocellular bile acid transport: cross talk between bile acids and second messengers.

From cells to organs: building polarized tissue.

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1403-1408

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10.1073/PNAS.1018376108

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108

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Jennifer Lippincott-Schwartz

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49741918

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21220320

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3029747

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