Characterization of the human factor VIII procoagulant protein with a heterologous precipitating antibody.
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Secretion of coagulant factor VIII activity and antigen by in vitro cultivated rat liver sinusoidal endothelial cellsDefining 'full-length' recombinant factor VIII: a comparative structural analysis.Localization of a factor VIII-inhibiting antibody epitope to a region between residues 338 and 362 of factor VIII heavy chain.Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.Structural model of porcine factor VIII and factor VIIIa molecules based on scanning transmission electron microscope (STEM) images and STEM mass analysisHemophilia as a defect of the tissue factor pathway of blood coagulation: effect of factors VIII and IX on factor X activation in a continuous-flow reactorThe use of chromatography to manufacture purer and safer plasma products.Heterogeneity of plasma von Willebrand factor multimers resulting from proteolysis of the constituent subunit.Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE).Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopesLocalization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIIIEpitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasminTwo distinct forms of Factor VIII coagulant protein in human plasma. Cleavage by thrombin, and differences in coagulant activity and association with von Willebrand factor.Isolation and characterization of human factor VIII: molecular forms in commercial factor VIII concentrate, cryoprecipitate, and plasma.Purification and characterization of a highly purified human factor VIII consisting of a single type of polypeptide chain.Comparison of in vitro and in vivo approaches to studying brain colonization by breast cancer cells.Potency and mass of factor VIII in FVIII productsLocalization of human factor FVIII inhibitor epitopes to two polypeptide fragments.Purified human factor VIII procoagulant protein: comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogs.Production and Purification of Rabbit's Polyclonal Antibody Against Factor VIII.Production of recombinant coagulation proteins.Synthesis of factor VIII by endothelial cells.Pharmacological activity of the C-terminal and N-terminal domains of secretory leukoprotease inhibitor in vitroProduct-dependent anti-factor VIII antibodies.Viral safety of a pasteurized, monoclonal antibody-purified factor VIII concentrate in previously untreated haemophilia A patients.Factor VIII polypeptide specificity of monoclonal anti-factor VIII antibodies.Purification of six human vitamin K-dependent proteins in a single chromatographic step using immunoaffinity columns.In vitro factor VIII recovery during the delivery of ultrapure factor VIII concentrate by continuous infusion.Proteolysis of factor VIII heavy chain polypeptides in plasma and concentrates.Factor VIII heavy chain polypeptides in plasma and concentrates.Evidence for a von Willebrand factor defect in factor VIII binding in three members of a family previously misdiagnosed mild haemophilia A and haemophilia A carriers: consequences for therapy and genetic counselling.Monoclonal antibodies to factor VIII: their application in immunoblotting for the visualization of factor VIII in therapeutic concentrates and plasma.Production of factor VIII deficient plasma by immunodepletion using three monoclonal antibodies.Radioimmunoassay for quantitative measurement of factor VIII-heavy chain.
P2860
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P2860
Characterization of the human factor VIII procoagulant protein with a heterologous precipitating antibody.
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年学术文章
@wuu
1982年学术文章
@zh-cn
1982年学术文章
@zh-hans
1982年学术文章
@zh-my
1982年学术文章
@zh-sg
1982年學術文章
@yue
1982年學術文章
@zh
1982年學術文章
@zh-hant
name
Characterization of the human ...... logous precipitating antibody.
@ast
Characterization of the human ...... logous precipitating antibody.
@en
type
label
Characterization of the human ...... logous precipitating antibody.
@ast
Characterization of the human ...... logous precipitating antibody.
@en
prefLabel
Characterization of the human ...... logous precipitating antibody.
@ast
Characterization of the human ...... logous precipitating antibody.
@en
P2860
P356
P1476
Characterization of the human ...... logous precipitating antibody.
@en
P2093
C A Fulcher
T S Zimmerman
P2860
P304
P356
10.1073/PNAS.79.5.1648
P407
P577
1982-03-01T00:00:00Z