Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency. - Wikidata - awgldk - TriplyDB

Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency.

Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency.

http://www.wikidata.org/entity/Q34572866

about

PI3K and cancer: lessons, challenges and opportunities mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3 Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities.Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2 Targeting mTOR/p70S6K/glycolysis signaling pathway restores glucocorticoid sensitivity to 4E-BP1 null Burkitt Lymphoma Recent progress in targeting cancer.Metabolic stress in autophagy and cell death pathways The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements.Metabolic regulation of T lymphocytes.A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL)Increased concentrations of fructose 2,6-bisphosphate contribute to the Warburg effect in phosphatase and tensin homolog (PTEN)-deficient cells.Emerging roles of p53 and other tumour-suppressor genes in immune regulation The application of mRNA-based gene transfer in mesenchymal stem cell-mediated cytotoxicity of glioma cells.Hypoxia-inducible factors and their roles in energy metabolism.Cellular metabolism on T-cell development and function.Cellular energy metabolism in T-lymphocytes.Oncogenic PTEN functions and models in T-cell malignancies.RICTOR involvement in the PI3K/AKT pathway regulation in melanocytes and melanoma Rapamycin-enhanced mitomycin C-induced apoptotic death is mediated through the S6K1-Bad-Bak pathway in peritoneal carcinomatosis S6K1 determines the metabolic requirements for BCR-ABL survival.Regulators of Glucose Metabolism in CD4(+) and CD8(+) T Cells.Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia.Regulation of T cell homeostasis and responses by pten.Molecular Characterization and Expression Analysis of S6K1 in Cashmere Goats (Capra hircus).Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia.PTEN antagonises Tcl1/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis.Evolving Significance and Future Relevance of Anti-Angiogenic Activity of mTOR Inhibitors in Cancer Therapy.Regulatory Roles of Mitochondrial Ribosome in Lung Diseases and Single Cell Biology.Inhibition of S6K1 enhances dichloroacetate-induced cell death.

P2860

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P2860

Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency.

http://www.wikidata.org/entity/Q34572866

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

@ast

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

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Requirement for ribosomal prot ...... ce induced by Pten deficiency.

@nl

type

label

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

@ast

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

@en

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

@nl

prefLabel

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

@ast

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

@en

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

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P1433

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P356

PNAS.1013629108

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Requirement for ribosomal prot ...... ce induced by Pten deficiency.

@en

P2093

Catherine A Gallo

http://www.w3.org/2001/XMLSchema#string

David R Plas

http://www.w3.org/2001/XMLSchema#string

Jennifer F Barger

http://www.w3.org/2001/XMLSchema#string

Preeti Tandon

http://www.w3.org/2001/XMLSchema#string

Shikha Khatri

http://www.w3.org/2001/XMLSchema#string

P2860

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

Loss of PTEN facilitates HIF-1-mediated gene expression

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

P304

2361-2365

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scholarly article

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10.1073/PNAS.1013629108

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P433

6

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108

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P50

Hasmik Yepiskoposyan

P577

2011-01-24T00:00:00Z

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49781555

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21262837

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3038712

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