Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin. - Wikidata - awgldk - TriplyDB

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin.

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin.

http://www.wikidata.org/entity/Q34574600

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Interactions of the human MCM-BP protein with MCM complex components and Dbf4 CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol (epsilon}, and GINS in budding yeast The replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplication How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?Cdc7-Dbf4 and the human S checkpoint response to UVC Mechanism of cancer cell death induced by depletion of an essential replication regulator Crystal structure of human CDC7 kinase in complex with its activator DBF4 The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3 Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination.The replication initiation protein Sld2 regulates helicase assembly.Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress.An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication Initiation The potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffolds DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach Global gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancer Cdc7-Dbf4 is a gene-specific regulator of meiotic transcription in yeast Dbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth.Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin.Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae.The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 Drf1-dependent kinase interacts with Claspin through a conserved protein motif.An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2-7 Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damage Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA.Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components Rif1 is a global regulator of timing of replication origin firing in fission yeast.Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication Sister acts: coordinating DNA replication and cohesion establishment.MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells.Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells The PS1 hairpin of Mcm3 is essential for viability and for DNA unwinding in vitro.Characterization of a Drosophila ortholog of the Cdc7 kinase: a role for Cdc7 in endoreplication independent of Chiffon.Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation.Dpb11 protein helps control assembly of the Cdc45·Mcm2-7·GINS replication fork helicase.The Cdc45·Mcm2-7·GINS protein complex in trypanosomes regulates DNA replication and interacts with two Orc1-like proteins in the origin recognition complex.Enabling association of the GINS protein tetramer with the mini chromosome maintenance (Mcm)2-7 protein complex by phosphorylated Sld2 protein and single-stranded origin DNA.Geminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cells

P2860

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P2860

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin.

http://www.wikidata.org/entity/Q34574600

description

2006 nî lūn-bûn

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2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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type

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Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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prefLabel

Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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Journal of Biological Chemistry

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Phosphorylation of MCM4 by Cdc ...... n with Cdc45 on the chromatin.

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P2093

Ai Ishii

http://www.w3.org/2001/XMLSchema#string

Chika Taniyama

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Etsuko Matsui

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Hisao Masai

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Jung-Min Kim

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Katsuyuki Tamai

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Keiko Ogino

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Ken-Ichi Arai

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Kiyoshi Ohtani

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Naoko Kakusho

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P2860

A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells

A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7

A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases

Biochemical analysis of the intrinsic Mcm4-Mcm6-mcm7 DNA helicase activity

CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein

The structure and function of MCM from archaeal M. Thermoautotrophicum

Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin

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39249-39261

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10.1074/JBC.M608935200

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51

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281

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6748556

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17046832

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phosphorylation