Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae.
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Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repairHuman CtIP promotes DNA end resectionTargeting DNA topoisomerase II in cancer chemotherapyInhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer TherapyCaenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediatesTyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damageRad50 is dispensable for the maintenance and viability of postmitotic tissuesDNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeDNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial InhibitionIdentification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assayGEN1/Yen1 and the SLX4 complex: Solutions to the problem of Holliday junction resolution.MRE11 function in response to topoisomerase poisons is independent of its function in double-strand break repair in Saccharomyces cerevisiaeSelective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage.Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).Transcriptomic and proteomic profiling of maize embryos exposed to camptothecinProcessing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes.Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesionsSynthetic viability genomic screening defines Sae2 function in DNA repair.Neuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 (TDP1).Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonucleaseTopoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae.Role for topoisomerase 1 in transcription-associated mutagenesis in yeastPoly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells.Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) inhibitorsPhosphorylation of Sae2 Mediates Forkhead-associated (FHA) Domain-specific Interaction and Regulates Its DNA Repair Function.Sumoylation influences DNA break repair partly by increasing the solubility of a conserved end resection protein.DNA repair factor MRE11/RAD50 cleaves 3'-phosphotyrosyl bonds and resects DNA to repair damage caused by topoisomerase 1 poisons.Repair synthesis step involving ERCC1-XPF participates in DNA repair of the Top1-DNA damage complex.Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes.Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 ActivityTyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells.Topoisomerase I-dependent viability loss in saccharomyces cerevisiae mutants defective in both SUMO conjugation and DNA repair.A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 geneFunctional interactions between Sae2 and the Mre11 complex.Repair of topoisomerase I-mediated DNA damage.Tyrosyl-DNA phosphodiesterase as a target for anticancer therapyEnhancing drug accumulation in Saccharomyces cerevisiae by repression of pleiotropic drug resistance genes with chimeric transcription repressors.Choreography of recombination proteins during the DNA damage response.4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and related novel steroid derivatives as tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors.
P2860
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P2860
Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@ast
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@en
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@nl
type
label
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@ast
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@en
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@nl
prefLabel
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@ast
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@en
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@nl
P2093
P2860
P1433
P1476
Multiple endonucleases functio ...... s in Saccharomyces cerevisiae.
@en
P2093
Changchun Deng
Dongqing You
J Martin Brown
James A Brown
P2860
P304
P356
10.1534/GENETICS.104.028795
P407
P577
2005-04-16T00:00:00Z