The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. - Wikidata - awgldk - TriplyDB

The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo.

The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo.

http://www.wikidata.org/entity/Q34618563

about

MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion.Role of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiology A functional genomic screen combined with time-lapse microscopy uncovers a novel set of genes involved in dorsal closure of Drosophila embryos Solution structure and backbone dynamics of the AF-6 PDZ domain/Bcr peptide complex The PDZ protein Canoe/AF-6 links Ras-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting with Ras, Notch and Dishevelled.Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway.Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells.Control of cell adhesion dynamics by Rap1 signaling.Self-association mediated by the Ras association 1 domain of AF6 activates the oncogenic potential of MLL-AF6.Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1 The single Drosophila ZO-1 protein Polychaetoid regulates embryonic morphogenesis in coordination with Canoe/afadin and Enabled.Genetic ablation of afadin causes mislocalization and deformation of Paneth cells in the mouse small intestinal epithelium.Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation.The Rap1-Rgl-Ral signaling network regulates neuroblast cortical polarity and spindle orientation.Fine-Tuning of the Actin Cytoskeleton and Cell Adhesion During Drosophila Development by the Unconventional Guanine Nucleotide Exchange Factors Myoblast City and Sponge.Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature.Discontinuities in Rap1 activity determine epithelial cell morphology within the developing wing of Drosophila.The Rap GTPase activator Drosophila PDZ-GEF regulates cell shape in epithelial migration and morphogenesis.The small GTPase Rap1 is a modulator of Hedgehog signaling.Under construction: building the macromolecular superstructure and signaling components of an electrical synapse.Crumbs is an essential regulator of cytoskeletal dynamics and cell-cell adhesion during dorsal closure in Drosophila.Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo.Distinct Rap1 activity states control the extent of epithelial invagination via α-catenin.The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction.Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila New insights into the biological effects of anthrax toxins: linking cellular to organismal responses Requirement of the Caenorhabditis elegans RapGEF pxf-1 and rap-1 for epithelial integrity Talin autoinhibition is required for morphogenesis.The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye A big new job for small GTPases Rap1 acts via multiple mechanisms to position Canoe and adherens junctions and mediate apical-basal polarity establishment.Rap1, Canoe and Mbt cooperate with Bazooka to promote zonula adherens assembly in the fly photoreceptor.

P2860

8c02007bc9e5ae495684cc23164f5582ae1fea94 fef3ac9a826d431c73ba2b2e01670b7429fcda56

P248

Q24540244-DFAE260D-A6D0-45E1-BA7A-48E0E4C250AE Q27003242-B4CC26FD-4CE6-4D04-90E6-A6AEA2C8A319 Q27332111-071124B5-3E5D-4740-9359-201A9A7ADE3C Q27644666-7F41150B-C95A-4088-B4C4-CBB640BBBFAA Q33267326-F8C8D770-C9C9-4CD2-B782-E0985EA9A49D Q33552508-8816E0E6-D620-4513-A83B-FB1395E6E64E Q33647027-A81DE18A-C97E-47D2-BE05-0765B61ABA66 Q33740476-AA62713E-4FA0-4360-AED2-C0FDE5402C34 Q33997220-801C081C-1B4A-4C90-B874-AB7AC0AC85F3 Q34016597-9EDDBC66-DA40-4C20-A884-67F33B6A3F64 Q35041603-608BDB0F-7475-4867-BB9F-BF81B8CD6511 Q35353951-FDF603FE-7531-43E6-896C-9E87AE8B4D91 Q35503704-26657A98-CF59-4691-A477-6110A2C78EDA Q35670607-5BA61585-C280-461C-B018-614C7A5EF25C Q35821089-B4554B53-1B45-4113-A334-4BAA1D7C344B Q35880860-CC1E06AC-289A-47D4-BC3B-469AF858A071 Q36177325-41430433-43E5-435C-AF28-2E5FB63A69C9 Q36315901-5FB4902C-69CF-4F1F-826E-D993411F97F1 Q36395540-5B77A519-4C84-4293-BF54-CBCF767F3F47 Q36423270-B3179998-17F9-4C6C-884E-1C17C460616E Q36479371-FC561B83-2114-49B3-B73E-7B39CDD3784F Q36717388-F76B78FD-24E7-4073-B8D7-F82B25896331 Q37089179-FEF55919-A243-4D50-B03F-B3EACB5C49BD Q37267715-D5960262-8ACA-4472-AFF3-C0D5F1783647 Q37307510-0C0C846A-8503-4021-B049-092D795A635E Q37315655-BE22AE61-7567-4F0E-9CA5-CD8793E430C9 Q37935265-3E32FB05-4A3A-469C-A405-4A52BE2F4163 Q40741931-BF8C9941-2EB2-4888-A90B-BF12313A1CC1 Q41853229-0BB03A32-4FB5-4E25-ABFF-6506B25FA864 Q41966646-C575D09E-1118-4CDA-9F1F-C0B881C076FC Q42325462-DD4F575D-0922-4259-808C-AC8DA2D6A0FA Q48183354-3E4EDC2E-3CB1-4C37-B704-DAD8CA2A018A Q54982493-0D7A3E10-914C-4AD3-9EB3-FCD6973C890B

P2860

The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo.

http://www.wikidata.org/entity/Q34618563

description

2003 nî lūn-bûn

@nan

2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@ast

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@en

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@nl

type

label

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@ast

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@en

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@nl

prefLabel

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@ast

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@en

The AF-6 homolog canoe acts as ...... sure of the Drosophila embryo.

@nl

P1433

Q34618563-C516568F-1E48-402F-8F70-763BC1C43A76

P1476

Q34618563-5EC6F258-C37D-4575-8044-0B8C6257AA24

P2093

Q34618563-068AD361-7ACE-4904-8C7F-1A585EEC9982

Q34618563-1177C823-77FD-4D72-A8CE-96048BF18E28

Q34618563-31507B93-1ADA-4473-85D3-09DC63770D2B

Q34618563-608ACA25-C312-45DD-9153-F0AFDAC1A042

Q34618563-6BB54723-5822-4FBB-A09A-B3F8DB24863D

Q34618563-921E5957-361E-4CAD-AFAD-87A27116A04A

Q34618563-98DFBE36-E0D6-4280-BACE-87A87C389E08

Q34618563-E1E0E9A8-E9E7-43B1-9B89-92E5105CF7B8

P2860

Q34618563-0327D5AC-8C41-48D5-9C15-395D765F9B33

Q34618563-140FBAD7-BA9D-451F-8F2D-AD005EC488A8

Q34618563-17E60581-4D0D-4F23-80D6-60F631538079

Q34618563-1BD213FA-28DF-472B-8487-758DB7DB1B5E

Q34618563-27F0018C-5A7A-4596-B7DE-5A70BF65B54B

Q34618563-47263B21-1274-4417-9E1E-1B8C997C34DA

Q34618563-5115E88A-3500-46CE-8B9B-189B5EF89DAB

Q34618563-581D7D51-F804-4936-AC6B-7940FF4E4146

Q34618563-5EF6AD2A-3205-4A77-87B5-4A59FAA1EDF0

Q34618563-64B2966A-6B03-4B2F-8F30-F906E908DAA6

P304

Q34618563-92FC4FE0-9549-45A1-964F-B7FB4100BDA0

P31

Q34618563-BB067E07-1177-4539-BF87-1F4D30A0C08A

P407

Q34618563-99836A4B-213C-48C4-9CD5-23B6DCB547F6

P433

Q34618563-5FE236E7-61DA-41E5-9CD1-494C22D9FE4B

P478

Q34618563-6205F431-4111-482E-93B7-EB001786485A

P50

Q34618563-6B1DC0FB-486F-4B80-BC23-4CF25810FBEB

P577

Q34618563-67FF7D9A-532E-4BBC-80A7-AA2257E8BF15

P698

Q34618563-2B2B7D79-CEC2-4C9B-AFC4-A52C7056BE07

P921

Q34618563-C2381AF3-3C86-43A1-A3BB-CAC2B1DCEF2D

P932

Q34618563-1119BBBF-7573-4E2C-85E7-26B0F0BE8DCA

P1433

P1476

The AF-6 homolog canoe acts as ...... osure of the Drosophila embryo

@en

P2093

Benjamin Boettner

http://www.w3.org/2001/XMLSchema#string

Hong Qing Fan

http://www.w3.org/2001/XMLSchema#string

Linda Van Aelst

http://www.w3.org/2001/XMLSchema#string

Michael Heke

http://www.w3.org/2001/XMLSchema#string

Phoebe Harjes

http://www.w3.org/2001/XMLSchema#string

Satoshi Ishimaru

http://www.w3.org/2001/XMLSchema#string

Ulrike Gaul

http://www.w3.org/2001/XMLSchema#string

Yi Qin

http://www.w3.org/2001/XMLSchema#string

P2860

M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6

Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion

Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

A ras-related gene with transformation suppressor activity

Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.

The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily

The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain

RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

P304

159-169

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

165

http://www.w3.org/2001/XMLSchema#string

P50

P577

2003-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

14504224

http://www.w3.org/2001/XMLSchema#string

P921

P932

1462758

http://www.w3.org/2001/XMLSchema#string