APC/C(Cdc20) targets E2F1 for degradation in prometaphase. - Wikidata - awgldk - TriplyDB

APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

http://www.wikidata.org/entity/Q34619596

about

Cell cycle control of Wnt/β-catenin signalling by conductin/axin2 through CDC20 Deregulation of Rb-E2F1 axis causes chromosomal instability by engaging the transactivation function of Cdc20-anaphase-promoting complex/cyclosome.Largazole Arrests Cell Cycle at G1 Phase and Triggers Proteasomal Degradation of E2F1 in Lung Cancer Cells.The Drosophila MCPH1-B isoform is a substrate of the APCCdh1 E3 ubiquitin ligase complex.E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network A data-driven, mathematical model of mammalian cell cycle regulation.Regulation of E2F1 by APC/C Cdh1 via K11 linkage-specific ubiquitin chain formation.Regulation of E2 promoter binding factor 1 (E2F1) transcriptional activity through a deubiquitinating enzyme, UCH37.Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression.POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.Coordinated regulation of p31(Comet) and Mad2 expression is required for cellular proliferation CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes.Processive ubiquitin chain formation by the anaphase-promoting complex.Flipping the switch from g1 to s phase with e3 ubiquitin ligases Oncoprotein stabilization in brain tumors.E2F Transcription Factors Control the Roller Coaster Ride of Cell Cycle Gene Expression.Small compound bigelovin exerts inhibitory effects and triggers proteolysis of E2F1 in multiple myeloma cells.Logical model specification aided by model-checking techniques: application to the mammalian cell cycle regulation.Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.Expression and prognostic value of E2F activators in NSCLC and subtypes: a research based on bioinformatics analysis.DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues.Rbf1 degron dysfunction enhances cellular DNA replication Unbiased transcriptome signature of in vivo cell proliferation reveals pro- and antiproliferative gene networks Regulation of E2F1 Transcription Factor by Ubiquitin Conjugation.The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1.The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.

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P2860

APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

http://www.wikidata.org/entity/Q34619596

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

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APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

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type

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APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

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APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

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prefLabel

APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

@ast

APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

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APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

@en

P2093

Carol Prives

http://www.w3.org/2001/XMLSchema#string

Elizabeth M Kass

http://www.w3.org/2001/XMLSchema#string

Emmy W Verschuren

http://www.w3.org/2001/XMLSchema#string

Marshall Urist

http://www.w3.org/2001/XMLSchema#string

Masha V Poyurovsky

http://www.w3.org/2001/XMLSchema#string

Matthew K Summers

http://www.w3.org/2001/XMLSchema#string

Melissa J Peart

http://www.w3.org/2001/XMLSchema#string

Peter K Jackson

http://www.w3.org/2001/XMLSchema#string

P2860

Chk2 activates E2F-1 in response to DNA damage

Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

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3956-3964

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scholarly article

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10.4161/CC.9.19.13162

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19

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9

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P577

2010-10-26T00:00:00Z

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47429843

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20948288

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3047753

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