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Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditionsThe Sin3a repressor complex is a master regulator of STAT transcriptional activitySTAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasisThe cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3Cucurbitacins - a promising target for cancer therapyLoss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expressionRegulation of translocator protein 18 kDa (TSPO) expression in health and disease statesMutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomasOverexpression of PIAS3 suppresses cell growth and restores the drug sensitivity of human lung cancer cells in association with PI3-K/Akt inactivationStable expression of constitutively-activated STAT3 in benign prostatic epithelial cells changes their phenotype to that resembling malignant cellsKnockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cellsThe Obesity-Breast Cancer Conundrum: An Analysis of the IssuesSTATs: An Old Story, Yet MesmerizingTargeting the tumor microenvironment: JAK-STAT3 signalingNormal and neoplastic urothelial stem cells: getting to the root of the problemThe consequences of selective inhibition of signal transducer and activator of transcription 3 (STAT3) tyrosine705 phosphorylation by phosphopeptide mimetic prodrugs targeting the Src homology 2 (SH2) domainTherapeutic strategies for the clinical blockade of IL-6/gp130 signalingSTAT3: A Novel Molecular Mediator of Resistance to ChemoradiotherapyCADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity.Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancerThe role of STAT3 in autophagyMyeloid-derived suppressor cells as regulators of the immune systemSTAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3.The expression of microRNA-203 during human skin morphogenesisTargeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solutionPAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesisGaliellalactone inhibits stem cell-like ALDH-positive prostate cancer cellsNuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTPScoparone exerts anti-tumor activity against DU145 prostate cancer cells via inhibition of STAT3 activityEriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell CarcinomaDistinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemiaTranscriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cellsSTAT3 mediates resistance of CD44(+)CD24(-/low) breast cancer stem cells to tamoxifen in vitro.Menin and RNF20 recruitment is associated with dynamic histone modifications that regulate signal transducer and activator of transcription 1 (STAT1)-activated transcription of the interferon regulatory factor 1 gene (IRF1).Rationale and early clinical data on IL-17 blockade in psoriasis.Prediction and experimental validation of novel STAT3 target genes in human cancer cellsMolecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein.Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Stat proteins and oncogenesis.
@ast
Stat proteins and oncogenesis.
@en
Stat proteins and oncogenesis.
@nl
type
label
Stat proteins and oncogenesis.
@ast
Stat proteins and oncogenesis.
@en
Stat proteins and oncogenesis.
@nl
prefLabel
Stat proteins and oncogenesis.
@ast
Stat proteins and oncogenesis.
@en
Stat proteins and oncogenesis.
@nl
P2860
P356
P1476
Stat proteins and oncogenesis.
@en
P2093
Jacqueline Bromberg
P2860
P304
P356
10.1172/JCI0215617
P407
P577
2002-05-01T00:00:00Z