Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis.
about
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturationGoblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine.Mammalian Merkel cells are descended from the epidermal lineageEpidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasisMerkel cells are essential for light-touch responses.Lineage selection and plasticity in the intestinal cryptEpigenetic silencing of Notch signaling in gastrointestinal cancersPaneth cells in intestinal homeostasis and tissue injuryGenerating human intestinal tissues from pluripotent stem cells to study development and diseaseThe quest for restoring hearing: Understanding ear development more completely.Epigenetic regulation of the intestinal epitheliumAtonal homolog 1 is a tumor suppressor geneDelta1 expression, cell cycle exit, and commitment to a specific secretory fate coincide within a few hours in the mouse intestinal stem cell systemConditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factorDissecting the molecular basis of organ of Corti development: Where are we now?The Role of Atonal Factors in Mechanosensory Cell Specification and FunctionUnderstanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation.Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditory nuclei.The tumor suppressor Apc controls planar cell polarities central to gut homeostasis.Notch as a Driver of Gastric Epithelial Cell Proliferation.Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea.Notch: architect, landscaper, and guardian of the intestine.Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity.Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fateA novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability.Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival.Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene.Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis.Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signalingIntestinal development and differentiation.The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in miceMapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP alleleTargeting Notch Signaling in Colorectal Cancer.Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational studyIn vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development.Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colonGenetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repressionVertebrate intestinal endoderm development.
P2860
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P2860
Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Intestine-specific ablation of ...... role in cellular homeostasis.
@ast
Intestine-specific ablation of ...... role in cellular homeostasis.
@en
Intestine-specific ablation of mouse atonal homolog 1
@nl
type
label
Intestine-specific ablation of ...... role in cellular homeostasis.
@ast
Intestine-specific ablation of ...... role in cellular homeostasis.
@en
Intestine-specific ablation of mouse atonal homolog 1
@nl
prefLabel
Intestine-specific ablation of ...... role in cellular homeostasis.
@ast
Intestine-specific ablation of ...... role in cellular homeostasis.
@en
Intestine-specific ablation of mouse atonal homolog 1
@nl
P2093
P1433
P1476
Intestine-specific ablation of ...... role in cellular homeostasis.
@en
P2093
Barbara Antalffy
Michael A Helmrath
Susan J Henning
Vincent Y-C Wang
P304
P356
10.1053/J.GASTRO.2007.03.047
P407
P577
2007-03-24T00:00:00Z